21730-93-8 Usage
Description
L-Threonolactone, also known as A786990, is a butan-4-olide with dihydrofuran-2-one substituted at C-3 and C-4 by hydroxy groups, specifically the 3R,4S-diastereomer. It is formed during the autoxidation of L-Ascorbic acid, a compound that plays a crucial role in various enzymatic reactions within the body and is responsible for scavenging free radicals to prevent oxidative damage to cells.
Uses
Used in Pharmaceutical Industry:
L-Threonolactone is used as a pharmaceutical compound for its potential therapeutic applications. It is derived from L-Ascorbic acid, which is essential for numerous enzymatic reactions in the body and has antioxidant properties that protect cells from oxidative damage.
Used in Antioxidant Applications:
L-Threonolactone is used as an antioxidant agent due to its connection with L-Ascorbic acid, which is known for scavenging free radicals and preventing oxidative damage to cells. This property makes L-Threonolactone a valuable component in the development of antioxidant therapies and products.
Used in Enzymatic Reactions:
L-Threonolactone is used as a component in various enzymatic reactions within the body, as it is formed during the autoxidation of L-Ascorbic acid. This involvement in enzymatic processes highlights its importance in maintaining proper cellular function and overall health.
Used in Research and Development:
L-Threonolactone is used as a research compound for studying the autoxidation process of L-Ascorbic acid and its effects on cellular processes. This research can lead to a better understanding of the role of L-Ascorbic acid and L-Threonolactone in cellular health and the development of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 21730-93-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,3 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21730-93:
(7*2)+(6*1)+(5*7)+(4*3)+(3*0)+(2*9)+(1*3)=88
88 % 10 = 8
So 21730-93-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H22O4Si2/c1-15(2,3)13-8-7-12-10(11)9(8)14-16(4,5)6/h8-9H,7H2,1-6H3
21730-93-8Relevant articles and documents
Substrate-like water soluble lipase inhibitors from Filipendula kamtschatica
Kato, Eisuke,Yama, Michitsugu,Nakagomi, Ryo,Shibata, Toshiro,Hosokawa, Keizo,Kawabata, Jun
supporting information, p. 6410 - 6412 (2012/11/07)
Filipendula kamtschatica is a plant utilized as a traditional medicine by Ainu people in Japan, but its chemical constituents are not much studied. Pancreatic lipase inhibitors are a promising tool for the treatment of obesity. We searched for natural lipase inhibitors from F. kamtschatica and two new compounds were isolated along with the known flavonoid glycoside. The structure elucidation of new compounds revealed these two to be 2-O-caffeoyl-4-O-galloyl- l-threonic acid and 3-O-caffeoyl-4-O-galloyl-l-threonic acid, which can be recognized as a pancreatic lipase's substrate-like structure. The isolated compounds all showed an inhibitory activity against porcine pancreatic lipase and one of the isomer, 3-O-caffeoyl-4-O-galloyl-l-threonic acid, possessed the most potent activity with IC50 value showing an order lower value compared to others. The substrate-like structure of the new compounds seemed to be important for their activity.
Autoxidation Reaction Mechanism for L-Ascorbic Acid-related Compounds in Methanol without Metal Ion Catalysis
Miyake, Noriko,Kurata, Tadao
, p. 811 - 813 (2007/10/03)
The autoxidation mechanism for L-ascorbic acid (ASA)-related compounds such as D-arabo-ascorbic acid (= erythorbic acid; ERA) and triose reductone (TR) in methanol without metal ion catalysis was studied.The oxidation reaction of these ASA-related compounds seems to proceed via the C(2) oxygen adduct of ERA (or TR) by a similar reaction mechanism to that of ASA. - Keywords: L-ascorbic acid; autoxidation; D-erythorbic acid; triose reductone; C(2) oxygen adduct
