217318-62-2Relevant articles and documents
PYRROLO 2,1,5-CD]INDOLIZINE DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES
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Page 17, (2008/06/13)
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Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives
Jorgensen, Anker Steen,Jacobsen, Poul,Christiansen, Lise Brown,Bury, Paul S.,Kanstrup, Anders,Thorpe, Susan M.,Narum, Lars,Wassermann, Karsten
, p. 2383 - 2386 (2007/10/03)
A series of pyrrolo[2,1,5-cd]indolizine derivatives has been synthesized and evaluated as ligands for the estrogen receptor. Properly substituted mono- and di-hydroxy derivatives showed binding in the low nanomolar range in accordance with their structural resemblance to estrogen. (C) 2000 Elsevier Science Ltd.