217438-93-2Relevant articles and documents
A new approach to asymmetric synthesis of β-amino alcohols by means of α-chirally protected amino alkyllithiums
Tomoyasu, Takahiro,Tomooka, Katsuhiko,Nakai, Takeshi
, p. 1147 - 1149 (2007/10/03)
A new, general synthetic approach to enantiopure α-amino ketones and syn-β-amino alcohols is described which employs the doubly chiral N-protected α-amino alkyllithiums generated via Pearson's transmetalative protocol as the key synthetic intermediates.