2178-03-2Relevant articles and documents
Rhodium(I)-catalyzed regiospecific dimerization of aromatic acids: Two direct C-H bond activations in water
Gong, Hang,Zeng, Huiying,Zhou, Feng,Li, Chao-Jun
, p. 5718 - 5721 (2015)
2,2'-Diaryl acids are key building blocks for some of the most important and high-performance polymers such as polyesters and polyamides (imides), as well as structural motifs of MOFs (metal-organic frameworks) and biological compounds. In this study, a direct, regiospecific and practical dimerization of simple aromatic acids to generate 2,2'-diaryl acids has been discovered, which proceeds through two rhodium-catalyzed C-H activations in water. This reaction can be easily scaled up to gram level by using only 0.4-0.6 mol% of the rhodium catalyst. As a proof-of-concept, the natural product ellagic acid was synthesized in two steps by this method. On the double: An efficient, regiospecific, and general oxidative dimerization of simple aryl acids to generate diaryl acids was developed. The reaction involves two direct aryl C-H activations catalyzed by rhodium, uses water as the solvent, and can be easily scaled up. The natural product ellagic acid was obtained in only two steps by using this method.
Bisoxazoline ligands with an axial-unfixed biaryl backbone: the effects of the biaryl backbone and the substituent at oxazoline ring on Cu-catalyzed asymmetric cyclopropanation
Zhang, Wanbin,Xie, Fang,Matsuo, Shigeaki,Imahori, Yuji,Kida, Toshiyuki,Nakatsuji, Yohji,Ikeda, Isao
, p. 767 - 777 (2007/10/03)
The synthesis of novel C2-symmetric bisoxazoline ligands with an axial-unfixed biaryl backbone and different substituents at the oxazoline ring is reported. The diastereomer equilibrium of these ligands in solution and their complexation behavi
