21784-96-3

Basic information

• Product Name: (Butyl)(p-tolyl) sulfide
• Synonyms: (Butyl)(p-tolyl) sulfide;1-(Butylthio)-4-methylbenzene;4-Methylphenylbutyl sulfide;Butyl 4-methylphenyl sulfide;Butyl(4-methylphenyl) sulfide;p-Tolylbutyl sulfide
• CAS NO: 21784-96-3
• Molecular Formula: C₁₁H₁₆S
• Molecular Weight: 180.3097
• Mol File: 21784-96-3.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 258.4°Cat760mmHg
• Flash Point: 107.9°C
• Appearance: /
• Density: 0.96g/cm³
• Vapor Pressure: 0.0222mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: (Butyl)(p-tolyl) sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: (Butyl)(p-tolyl) sulfide(21784-96-3)
• EPA Substance Registry System: (Butyl)(p-tolyl) sulfide(21784-96-3)

Safety Data

• Hazardous Substances Data: 21784-96-3(Hazardous Substances Data)

Usage

Description

(Butyl)(p-tolyl) sulfide, with the molecular formula C10H15S, is a type of sulfide, which is an organic compound containing sulfur. This specific sulfide consists of four carbon atoms, one sulfur atom, and a p-tolyl group, which is a substituent of toluene. It is a colorless to light yellow liquid with a strong odor and is known for its potential health hazards, such as skin and eye irritation and respiratory issues. (Butyl)(p-tolyl) sulfide is an important and versatile chemical compound with a wide range of industrial and pharmaceutical applications.

Uses

Used in Pharmaceutical Industry:
(Butyl)(p-tolyl) sulfide is used as a synthetic intermediate for the production of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the synthesis of different drugs, contributing to the development of new medications.
Used in Agrochemical Industry:
In the agrochemical industry, (Butyl)(p-tolyl) sulfide is utilized as a synthetic intermediate for the creation of various agrochemicals. Its properties make it suitable for use in the development of pesticides, herbicides, and other agricultural products to enhance crop protection and yield.
Used in Dye Industry:
(Butyl)(p-tolyl) sulfide is employed as a synthetic intermediate in the production of dyes. Its chemical structure plays a crucial role in the synthesis of a wide range of dyes used in various industries, such as textiles, plastics, and printing.
Used in Rubber Chemicals Production:
(Butyl)(p-tolyl) sulfide is used as a component in the production of rubber chemicals. Its properties make it an essential ingredient in the development of additives and other chemicals that improve the performance and durability of rubber products.
Used in Lubricants Production:
In the lubricants industry, (Butyl)(p-tolyl) sulfide is utilized in the production of various lubricants. Its unique chemical structure contributes to the development of high-quality lubricants that are used in various applications, such as automotive, industrial, and marine.
Overall, (Butyl)(p-tolyl) sulfide is a versatile and essential chemical compound with numerous applications across different industries, including pharmaceuticals, agrochemicals, dyes, rubber chemicals, and lubricants. Its unique properties and potential health hazards make it a compound of interest for further research and development in these fields.

InChI:InChI=1/C11H16S/c1-3-4-9-12-11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3

Upstream product

• 693-03-8 n-butyl magnesium bromide 
• 640-60-8 toluene-4-sulfonic acid phenyl ester 
• 60-29-7 diethyl ether 
• 108-88-3 toluene 
• 30506-35-5 butyl(p-tolyl)sulfoxide 
• 17627-00-8 S,S-dibutyl-N-p-tosylsulfilimine 
• 10486-08-5 sodium p-thiocresolate 
• 109-65-9 1-bromo-butane 
• 106-45-6 para-thiocresol 
• 5285-74-5 4-tolyl thiocyanate 
• 71-36-3 butan-1-ol 
• 109-79-5 n-butanethiol 
• 624-31-7 4-tolyl iodide 
• 629-45-8 dibutyl disulfide 

Downstream Products

• 620-84-8 4-methyldiphenylamine 
• 30506-35-5 (R)-1-(butylsulfinyl)-4-methylbenzene 
• 20288-49-7 (S)-1-(butylsulfinyl)-4-methylbenzene 
• 7569-36-0 1-(butylsulfonyl)-4-methylbenzene 
• 30506-35-5 butyl(p-tolyl)sulfoxide 

Relevant articles and documents

Nickel-Catalyzed Reductive Thiolation of Unactivated Alkyl Bromides and Arenesulfonyl Cyanides

The cross-electrophile coupling between unactivated alkyl bromides with arenesulfonyl cyanides catalyzed by Ni(acac)2under reductive conditions to form unsymmetrical sulfides is developed. This approach for sulfide synthesis is practical, relies on available, unfunctionalized materials such as alkyl (pseudo)halides, and is scalable. This catalytic strategy provides a complementary method for the preparation of unsymmetrical alkyl-aryl sulfides under mild conditions with good functional group tolerance.

Exploration of the mechanism and scope of the CuI/DABCO catalysed C–S coupling reaction

A cost effective and easily available CuI/DABCO catalytic system has been developed for the C–S cross-coupling reaction. This method is extremely useful for the thioetherification of aryl and heteroaryl halides, providing excellent yields and good chemoselectivity. We have also explored the mechanism of the reaction using DFT studies.

Synthesis method of thioether compounds

The invention discloses a synthesis method of thioether compounds. The method comprises steps as follows: phosphorus trichloride and a solvent with uniformly distributed sulfoxide compounds are mixeduniformly, after mixing, the mixture is subjected to a reaction at the temperature of 20-25 DEG C for 0.5-6 h, and the thioether compounds are obtained, wherein the solvent is acetonitrile. Compared with the prior art, the synthesis method has the advantages that raw materials are cheap and easy to obtain, a reducer is cheap and easy to obtain and store, and a series of thioether compounds can beobtained.