217952-09-5

Basic information

• Product Name: (R)-2-[((S)-2-Acetoxy-propionyl)-((S)-1-phenyl-ethyl)-amino]-propionic acid ethyl ester
• Synonyms: (R)-2-[((S)-2-Acetoxy-propionyl)-((S)-1-phenyl-ethyl)-amino]-propionic acid ethyl ester
• CAS NO: 217952-09-5
• Molecular Weight: 335.4
• Mol File: 217952-09-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-[((S)-2-Acetoxy-propionyl)-((S)-1-phenyl-ethyl)-amino]-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-[((S)-2-Acetoxy-propionyl)-((S)-1-phenyl-ethyl)-amino]-propionic acid ethyl ester(217952-09-5)
• EPA Substance Registry System: (R)-2-[((S)-2-Acetoxy-propionyl)-((S)-1-phenyl-ethyl)-amino]-propionic acid ethyl ester(217952-09-5)

Safety Data

• Hazardous Substances Data: 217952-09-5(Hazardous Substances Data)

Upstream product

• 63696-99-1 (S)-ethyl 2-(methylsulfonyloxy)propanoate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 36394-75-9 (S)-2-acetoxypropanoyl chloride 
• 84049-31-0 (2R,4S)-3-aza-2-methyl-4-phenyl-ethylpentanoate 

Downstream Products

• 174591-36-7 (3R,6S,1'S)-3,6-dimethyl-4-N-(1'-phenethyl)-1,4-morpholin-2,5-dione 

Relevant articles and documents

Stereoselective synthesis of uncommon α,α'-dialkyl-α- aminoacids. Part 1

The alkylation of the diastereomeric mixture of chiral morpholinone derivatives 4 and 5 occurs with good yield and trans induction. Cleavage of the alkylated products 6a,b,c,e gives enantiomerically pure uncommon (and sterically constrained) α,α'-dialkyl-α-aminoacids. The absolute configuration of the new stereocentres of 4, 5, 6 and 7 has been assigned on the basis of the 1H-NMR spectra and NOE measurements.