218167-54-5

Basic information

• Product Name: (R)-3-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-propylcarbamoyl)-propylcarbamoyl]-6-phenyl-hexanoic acid tert-butyl ester
• CAS NO: 218167-54-5
• Molecular Weight: 522.728
• Mol File: 218167-54-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-propylcarbamoyl)-propylcarbamoyl]-6-phenyl-hexanoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-propylcarbamoyl)-propylcarbamoyl]-6-phenyl-hexanoic acid tert-butyl ester(218167-54-5)
• EPA Substance Registry System: (R)-3-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-propylcarbamoyl)-propylcarbamoyl]-6-phenyl-hexanoic acid tert-butyl ester(218167-54-5)

Safety Data

• Hazardous Substances Data: 218167-54-5(Hazardous Substances Data)

Upstream product

• 218167-61-4 (R)-3-((S)-1-Benzyloxycarbonyl-2,2-dimethyl-propylcarbamoyl)-6-phenyl-hexanoic acid tert-butyl ester 
• 156109-64-7 (2R)-2-[2-(tert-butoxy)-2-oxoethyl]-5-phenylpentanoic acid 
• 154092-64-5 tert-leucine benzyl ester 
• 2941-20-0 1-phenylpropylamine 
• 218167-60-3 (R)-3-((S)-1-Carboxy-2,2-dimethyl-propylcarbamoyl)-6-phenyl-hexanoic acid tert-butyl ester 

Downstream Products

• 343256-76-8 (R)-3-[(S)-2,2-Dimethyl-1-((R)-1-phenyl-propylcarbamoyl)-propylcarbamoyl]-6-phenyl-hexanoic acid 

Relevant articles and documents

Selectivity of inhibition of matrix metalloproteases MMP-3 and MMP-2 by succinyl hydroxamates and their carboxylic acid analogues is dependent on P3′ group chirality

Structure-activity relationships are described for a series of succinyl hydroxamic acids 1a-o and their carboxylic acid analogues 2a-o as inhibitors of matrix metalloproteases MMP-3 and MMP-2. For this series (P1′=(CH2)3Ph, P′2=t-Bu)