21834-92-4 Usage
Description
Cocal, also known as 5-Methyl-2-phenyl-2-hexenal, is a major volatile compound found in fermented flour paste. It is characterized by its distinct cocoa aroma and is commonly used in the creation of chocolate and cocoa-type flavors. Cocal can be synthesized from phenyl acetaldehyde and isopropyl acetaldehyde through an aldolic condensation process. Cocal is also naturally reported to be found in various sources such as roasted peanuts, peppermint oil, pork liver, cocoa, tea, roasted filberts, sesame seed, malt, wort, and cocoa liquor.
Uses
1. Used in Food Industry:
Cocal is used as a flavor enhancer for its cocoa aroma, contributing to the rich taste and scent of chocolate and cocoa-type products.
2. Used in Fragrance Industry:
Due to its distinct cocoa aroma, Cocal can be utilized as a component in the creation of various fragrances, particularly those with chocolate or cocoa notes.
3. Used in Cosmetics Industry:
Cocal's cocoa aroma can be employed in the development of scented products within the cosmetics industry, such as lotions, creams, and perfumes, to provide a pleasant and recognizable scent.
4. Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, Cocal's pleasant aroma could potentially be used in the pharmaceutical industry for the development of medications or supplements with a more appealing taste or smell.
Preparation
From phenyl acetaldehyde and isopropyl acetaldehyde by aldolic condensation
Check Digit Verification of cas no
The CAS Registry Mumber 21834-92-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,8,3 and 4 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 21834-92:
(7*2)+(6*1)+(5*8)+(4*3)+(3*4)+(2*9)+(1*2)=104
104 % 10 = 4
So 21834-92-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H16O/c1-11(2)8-9-13(10-14)12-6-4-3-5-7-12/h3-7,9-11H,8H2,1-2H3/b13-9+
21834-92-4Relevant articles and documents
van Praag et al.
, p. 1005,1007 (1968)
A practical total synthesis of plaunotol via highly Z-selective Wittig olefination of α-acetal ketones
Tago, Keiko,Arai, Masami,Kogen, Hiroshi
, p. 2073 - 2078 (2007/10/03)
Plaunotol (1), a known antiulcer drug, is the most important component of the Thai folk medicinal plant, Plau-noi, which has remarkable antipeptic ulcer activity. Recently, it was found that plaunotol (1) has antibacterial activity against Helicobacter priori, a causative agent in gastric ulcers and gastric adenocarcinoma, for example. In our investigation of the practical synthesis of 1, we have developed an efficient method for stereoselective synthesis of trisubstituted olefins via a Z-selective Wittig reaction. The olefination of readily available aliphatic α-acetal ketones with triphenylphosphonium salts in the presence of a potassium base and 18-crown-6 ether proceeded with excellent Z-selectivity. The Z-selective olefination provides a useful method for the construction of a range of trisubstituted olefin moieties; the practical and stereoselective total synthesis of plaunotol (1) was achieved via this Wittig reaction.
