218621-20-6Relevant articles and documents
A convenient synthesis of α-alkoxycarbonyl-α, β-unsaturated trifluoromethyl ketones
Katsuyama, Isamu,Funabiki, Kazumasa,Matsui, Masaki,Muramatsu, Hiroshige,Shibata, Katsuyoshi
, p. 179 - 179 (1996)
α-Alkoxycarbonyl-α,β-unsaturated trifluoromethyl ketones are easily prepared by Knoevenagel condensation of aldehydes with trifluoroacetoacetates in the presence of silica gel functionalized with amino groups and p-toluenesulfonic acid. The method gives the products in moderate to good yields.