2187409-01-2 Usage
Description
6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)‐7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is a complex organic compound with a unique molecular structure. It is characterized by its tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide core, which is further modified by various functional groups, including an amino-oxopentyl chain and a methoxyphenyl group. 6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)‐7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide holds potential for various applications due to its structural diversity and functional groups.
Uses
Used in Pharmaceutical Industry:
6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)‐7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is used as a potential therapeutic agent for the prevention and treatment of venous thromboembolism. Its application is based on its ability to act as a potent, direct, selective, and orally active inhibitor of coagulation factor Xa, which plays a crucial role in the coagulation cascade.
Used in Orthopedic Surgery:
In the field of orthopedic surgery, this compound is used as a potential new oral coagulant for the prevention of venous thromboembolism in patients undergoing total hip or knee replacement surgeries. Its application is due to its effectiveness in inhibiting coagulation factor Xa, thereby reducing the risk of blood clot formation.
Used in Stroke Treatment:
6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)‐7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is also used in the treatment of patients with venous thromboembolic disorder or atrial fibrillation who have experienced a stroke. Its application is based on its ability to modulate the coagulation process and prevent further clot formation, which can be detrimental in the context of stroke.
Check Digit Verification of cas no
The CAS Registry Mumber 2187409-01-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,1,8,7,4,0 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 2187409-01:
(9*2)+(8*1)+(7*8)+(6*7)+(5*4)+(4*0)+(3*9)+(2*0)+(1*1)=172
172 % 10 = 2
So 2187409-01-2 is a valid CAS Registry Number.
2187409-01-2Relevant articles and documents
Preparation method of apixaban impurity
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Paragraph 0032; 0038; 0039; 0043, (2018/04/03)
The invention provides a preparation method of an apixaban impurity 6-(4-((5-amino-5-oxopentyl)amino)phenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazole[3,4-c]pyridine-3-formamide ( a compound 7). Compounds 1 and 2 are taken as starting materials, four-step reaction, namely substitution, N-terminal Boc protection, cyclization and alkaline hydrolysis, is carried out, so that the compound 7 (described in the specification) is obtained, and a reliable impurity reference substance is provided for research on quality control of apixaban.
