218927-23-2Relevant articles and documents
Cyclisation of meta-phenylene-bis-alanine derivatives
Ritzen, Andreas,Frejd, Torbjoern
, p. 3419 - 3424 (1998)
The cyclisation of a meta-phenylene-bis-alanine derivative with several different spacer moieties was investigated. A large difference in the ease of cyclisation was observed depending on which path of cyclisation was chosen. NMR studies indicate that the closed-loop molecules adopt folded conformations with the loop directly above the aromatic ring plane.