21894-28-0Relevant articles and documents
High static pressure alters spin trapping rates in solution. Dependence on the structure of nitrone spin traps
Sueishi, Yoshimi,Yoshioka, Daisuke,Yoshioka, Chiharu,Yamamoto, Shunzo,Kotake, Yashige
, p. 896 - 901 (2007/10/03)
Using a competitive spin trapping method, relative spin trapping rates were quantified for various short-lived radicals (methyl, ethyl, and phenyl radicals). High static pressure was applied to the competitive spin-trapping system by employing high-pressure electron spin resonance (ESR) equipment. Under high pressure (490 bar), spin trapping rate constants for alkyl and phenyl radicals increased by 10 to 40%, and the increase was dependent on the structure of nitrone spin traps. A maximum increase was obtained when tert-butyl(4-pyridinylmethylene)amine N-oxide (4-POBN) was used as a spin trap. Activation volumes (ΔΔV?) for the two spin trapping reactions were calculated to be -17-(-9) cm3 mol -1 for the 4-POBN system. The Royal Society of Chemistry 2006.
Mass spectrometry and electron paramagnetic resonance study of free radicals spontaneously formed in nitrone-peracid reactions
Sang, Hong,Janzen, Edward G.,Lewis, Brian H.
, p. 2358 - 2363 (2007/10/03)
Reactions of spin traps (C-phenyl N-tert-butyl nitrone (PBN) and 5,5-dimethyl-2-phenyl-1-pyrroline N-oxide (2-Ph-DMPO)) with peracids have been investigated by both mass spectrometry (MS) and electron paramagnetic resonance (EPR). The peracids m-chloroperbenzoic acid, perbenzoic acid, and perpropionic acid, which can be considered models of biological peracids produced during lipid peroxidation, were found to react with spin traps to spontaneously produce significant amount of aminoxyl radicals. The radical products, as well as the nonradical products were detected and their structures identified by EPR and/or MS. Mechanisms for the formation of these products are proposed.
Spin Trapping of Oxygen-centred Radicals by Substituted N-Benzylidene-tert-butylamine N-Oxides
Abe, Yukino,Seno, Shin-ya,Sakakibara, Kazuhisa,Hirota, Minoru
, p. 897 - 903 (2007/10/02)
Spin-trapping of oxygen-centred radicals (tert-butoxyl and carboxyl) by substituted N-benzylidene-tert-butylamine N-oxides (X-PBN) has been studied and the rates have been measured by means of EPR experiments.The experimental results revealed a substituent effect and are rationalized by an electron-transfer mechanism between the frontier orbitals of the reactants.The reaction pathway has been deduced from molecular-orbital and molecular-mechanics calculations.