21964-44-3Relevant articles and documents
Radical reactions of epoxy esters induced by titanocene chloride
Fernández-Mateos,Herrero Teijón,Rabanedo Clemente,Rubio González
, p. 7755 - 7758 (2006)
The reductive radical cyclizations of several epoxy esters have been achieved using titanocene chloride. The tether length from the initial radical to the carbonyl acceptor is the key of the reactions. We obtained products from radical cyclization onto carbonyl formate and products from formate and hydrogen elimination. The stereochemical outcome of the 5-exo radical cyclization of two diastereomers is reported. A radical cascade cyclization of an unsaturated epoxy formate is also described.
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Burton
, p. 248,252 (1930)
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β-Borylation of conjugated carbonyl compounds with silylborane or bis(pinacolato)diboron catalyzed by Au nanoparticles
Fragkiadakis, Michael,Kidonakis, Marios,Stratakis, Manolis
supporting information, p. 8921 - 8927 (2020/11/23)
Conjugated aldehydes and ketones undergo reaction with Me2PhSiBpin (pin: pinacolato) catalyzed by Au nanoparticles supported on TiO2 forming exclusively the β-borylation products, via the intermediate formation of the labile silaboration adducts. This chemoselectivity pathway is complementary to the so far known analogous reaction catalyzed by other metals, where β-silylation occurs instead. β-Borylation also occurs with pinBBpin under identical reaction conditions in a variety of conjugated carbonyl compounds, including esters and amides which are unreactive in their attempted Au-catalyzed silaboration. This journal is
Ruthenium-Catalyzed Direct Dehydrogenative Cross-Coupling of Allyl Alcohols and Acrylates: Application to Total Synthesis of Hydroxy β-Sanshool, ZP-Amide I, and Chondrillin
Dethe, Dattatraya H.,Nagabhushana, C. B.
supporting information, (2020/02/15)
Ru-catalyzed oxidative coupling of allyl alcohols and activated olefins has been developed by C(allyl)-H activation of allyl alcohols providing efficient and direct access to synthetically useful α,β-unsaturated enone intermediates. Synthetic utility of this method was demonstrated by its application to synthesis of bioactive natural products such as Hydroxy-β-sanshool, ZP-amide I, Chondrillin, Plakorin, and (+)-cis-Solamin A.
