219795-10-5Relevant articles and documents
Dications of fluorenylidenes. Electronic effects on the paratropicity/antiaromaticity of diphenylmethyl-substituted fluorenyl cations
Mills, Nancy S.,Malinky, Tiffany,Malandra, James L.,Burns, Ellen E.,Crossno, Peter
, p. 511 - 517 (1999)
Oxidation of para-substituted diphenylmethylidenefluorenes results in the formation of antiaromatic fluorenyl cations, as evidenced by the paratropic shift in the 1H NMR spectrum. The magnitude of the shift is affected by the nature of the remo
Ligand-Free Ru-Catalyzed Direct sp3 C-H Alkylation of Fluorene Using Alcohols
Shaikh, Moseen A.,Agalave, Sandip G.,Ubale, Akash S.,Gnanaprakasam, Boopathy
, p. 2277 - 2290 (2020/02/04)
The sp3 C-H alkylation of 9H-fluorene using alcohol and a Ru catalyst via the borrowing hydrogen concept has been described. This reaction was catalyzed by the [Ru(p-cymene)Cl2]2 complex (3 mol %) and exhibited a broad reaction scope with different alcohols, allowing primary and secondary alcohols to be employed as nonhazardous and greener alkylating agents with the formation of environmentally benign water as a byproduct. A variety of 9H-fluorene underwent selective and exclusive mono-C9-alkylation with primary alcohols in good to excellent isolated yield (26 examples, 50-92% yield), whereas this reaction with secondary alcohols in the absence of any external oxidants furnished the tetrasubstituted alkene as the major product. Furthermore, a base-mediated C-H hydroxylation of the synthesized 9H-fluorene derivatives afforded 9H-hydroxy-functionalized quaternary fluorene derivatives in excellent yield.
A double Suzuki approach for synthesis of substituted diarylmethylidenefluorenes
Ramana,Kishore Reddy, Bonthu K.,Reddy, Challa Nageswara,Gonnade, Rajesh G.,Gurjar, Mukund K.
, p. 127 - 128 (2008/03/13)
A convenient synthesis of substituted diarylmethylidenefluorene derivatives, using a double Suzuki reaction, is reported. Georg Thieme Verlag Stuttgart.
