2198-58-5 Usage
Description
N,N-Diethyl-p-phenylenediamine monohydrochloride, also known as DEPPD monohydrochloride, is an organic compound with the chemical formula C10H16ClN3. It is a colorless crystalline solid that is soluble in water and alcohol but insoluble in ether. DEPPD monohydrochloride is commonly used in various industries due to its unique properties and applications.
Uses
Used in Color Photography:
N,N-Diethyl-p-phenylenediamine monohydrochloride is used as a color film developer in the field of color photography. It plays a crucial role in the development process of color films, enabling the production of high-quality images with accurate color reproduction.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, DEPPD monohydrochloride has been studied for its potential applications in cancer research. It may be used as a chemical intermediate in the synthesis of compounds with anticancer properties, contributing to the development of novel therapeutic agents.
Used in Chemical Synthesis:
DEPPD monohydrochloride can be used as a starting material or intermediate in the synthesis of various organic compounds, including pharmaceuticals, dyes, and other specialty chemicals. Its versatile chemical structure allows for further functionalization and modification to create a wide range of products.
Used in Rubber Industry:
In the rubber industry, DEPPD monohydrochloride is used as an antiozonant and an antioxidant. It helps to protect rubber materials from degradation caused by exposure to oxygen, ozone, and other environmental factors, thereby enhancing the durability and longevity of rubber products.
Used in Pharmaceutical Industry:
DEPPD monohydrochloride may also find applications in the pharmaceutical industry, where it can be used as an intermediate in the synthesis of various drugs and active pharmaceutical ingredients. Its unique chemical properties make it a valuable building block for the development of new medications.
Contact allergens
A color film developer. It is an allergen and an irritant
in photographers. Cross-reactivity is possible with
Disperse Blue 124, Disperse Blue 106, and Disperse
red 17, but not with para-amino compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 2198-58-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,9 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2198-58:
(6*2)+(5*1)+(4*9)+(3*8)+(2*5)+(1*8)=95
95 % 10 = 5
So 2198-58-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H16N2/c1-3-12(4-2)10-7-5-9(11)6-8-10/h5-8H,3-4,11H2,1-2H3
2198-58-5Relevant articles and documents
Synthesis, Identification, and Structure-Activity Relationship Analysis of GATA4 and NKX2-5 Protein-Protein Interaction Modulators
Jumppanen, Mikael,Kinnunen, Sini M.,V?lim?ki, Mika J.,Talman, Virpi,Auno, Samuli,Bruun, Tanja,Boije Af Genn?s, Gustav,Xhaard, Henri,Aumüller, Ingo B.,Ruskoaho, Heikki,Yli-Kauhaluoma, Jari
supporting information, p. 8284 - 8310 (2019/10/11)
Transcription factors GATA4 and NKX2-5 directly interact and synergistically activate several cardiac genes and stretch-induced cardiomyocyte hypertrophy. Previously, we identified phenylisoxazole carboxamide 1 as a hit compound, which inhibited the GATA4-NKX2-5 transcriptional synergy. Here, the chemical space around the molecular structure of 1 was explored by synthesizing and characterizing 220 derivatives and structurally related compounds. In addition to the synergistic transcriptional activation, selected compounds were evaluated for their effects on transcriptional activities of GATA4 and NKX2-5 individually as well as potential cytotoxicity. The structure-activity relationship (SAR) analysis revealed that the aromatic isoxazole substituent in the southern part regulates the inhibition of GATA4-NKX2-5 transcriptional synergy. Moreover, inhibition of GATA4 transcriptional activity correlated with the reduced cell viability. In summary, comprehensive SAR analysis accompanied by data analysis successfully identified potent and selective inhibitors of GATA4-NKX2-5 transcriptional synergy and revealed structural features important for it.
INHIBITORS OF PROTEIN AGGREGATION
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Page/Page column 40, (2008/06/13)
The invention relates generally to the use of diaminophenothiazine compounds to inhibit or reverse the aggregation of synuclein, and for their use in the manufacture of medicaments for this purpose (e.g. for the treatment of Parkinson's Disease). Also provided are related methods of detecting or labelling of aggregated synuclein.
Aggregated dyes for radiation-sensitive elements
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, (2008/06/13)
A dispersion comprising an aqueous medium having dispersed therein an aggregated dye of the Formula (I): wherein X is oxygen or sulfur; R1-R4each independently represent an unsubstituted or substituted alkyl group, an unsubstituted or substituted aryl group or an unsubstituted or substituted heteroaryl group; L1, L2and L3each independently represent substituted or unsubstituted methine groups; M+represents a proton or an inorganic or organic cation; and n is 0, 1, 2 or 3 and wherein the aggregated dye in the dispersion has an absorption halfbandwidth of less than 55 nm.
