219879-85-3

Basic information

• Product Name: 2-pyridine
• Synonyms: 2-pyridine
• CAS NO: 219879-85-3
• Molecular Weight: 185.314
• Mol File: 219879-85-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-pyridine(219879-85-3)
• EPA Substance Registry System: 2-pyridine(219879-85-3)

Safety Data

• Hazardous Substances Data: 219879-85-3(Hazardous Substances Data)

Upstream product

• 109-06-8 α-picoline 
• 624-92-0 Dimethyldisulphide 

Downstream Products

• 1121-60-4 pyridine-2-carbaldehyde 

Relevant articles and documents

A study on the BF3-directed lithiation of 2-picoline and 2,3-lutidine

The lithiation of 2-picoline (1a) and 2,3-lutidine (1b) in diethyl ether has been investigated with and without prior complexation with BF3. The reactions of the BF3 adduct of these moieties (2a and 2b) with lithium diisopropylamide (LDA) and subsequent trapping with benzaldehyde or dimethyl disulfide gave products corresponding to exclusive lithiation at the α-methyl carbon. The yields obtained with these reactions were far superior to that obtained with the lithiation of uncomplexed 1a and 1b. The dilithiation of 2a and 2b has also been investigated and a convenient and efficient synthesis of the diiodo derivatives of 1,2-bis(pyridin-2-yl)ethane has been provided.