2201-35-6 Usage
Description
4-methoxyphencyclidine, 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine, also known as Methoxydine, is a novel analog of ketamine and phencyclidine. It is recognized for its pharmacological activity as an N-methyl-D-aspartate (NMDA) receptor antagonist. 4-methoxyphencyclidine , 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine has potential applications in various fields due to its interaction with the NMDA receptor, which plays a crucial role in several neurological processes.
Uses
Used in Pharmaceutical Industry:
4-methoxyphencyclidine, 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine is used as a pharmaceutical agent for its NMDA receptor antagonist properties. The compound's ability to modulate the NMDA receptor makes it a potential candidate for the treatment of various neurological and psychiatric disorders, such as chronic pain, anxiety, and depression.
Used in Research Applications:
In the field of scientific research, 4-methoxyphencyclidine, 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine serves as a valuable tool for studying the role of NMDA receptors in the central nervous system. Its use in research can help advance our understanding of the receptor's function and contribute to the development of new therapeutic strategies for related conditions.
Used in Drug Development:
4-methoxyphencyclidine, 1-[1-(4-methoxyphenyl)cyclohexyl]-piperidine is utilized in drug development as a lead compound for the creation of novel medications targeting the NMDA receptor. Its unique properties and interactions with the receptor make it a promising starting point for the design and synthesis of new drugs with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 2201-35-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,0 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2201-35:
(6*2)+(5*2)+(4*0)+(3*1)+(2*3)+(1*5)=36
36 % 10 = 6
So 2201-35-6 is a valid CAS Registry Number.
2201-35-6Relevant articles and documents
Novel analogues of ketamine and phencyclidine as NMDA receptor antagonists
Zarantonello, Paola,Bettini, Ezio,Paio, Alfredo,Simoncelli, Chiara,Terreni, Silvia,Cardullo, Francesco
, p. 2059 - 2063 (2011/04/24)
The identification of structurally novel analogues of ketamine and phencyclidine (PCP), as NMDA receptor antagonists, with low to moderate potency at GluN2A and GluN2B receptors is discussed. In particular, some examples, such as compounds 6 and 10, shows decreased calculated lipophilicity, when compared to PCP, while retaining moderate activity. Moreover, the germinal aryl amino substituted lactam ring, as exemplified in compounds 7-10 and 11-13, constitutes a novel scaffold with potential application in the design of biologically active compounds.
THE SYNTHESIS OF PHENCYCLIDINE AND OTHER 1-ARYLCYCLOHEXYLAMINES.
MADDOX,GODEFROI,PARCELL
, p. 230 - 235 (2007/10/04)
-
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.