22014-91-1

Basic information

• Product Name: Benzenemethanamine, N-(phenylmethyl)-N-2-propenyl-
• CAS NO: 22014-91-1
• Molecular Formula: C17H19N
• Molecular Weight: 237.345
• Mol File: 22014-91-1.mol
• Article Data: 33

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-(phenylmethyl)-N-2-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-(phenylmethyl)-N-2-propenyl-(22014-91-1)
• EPA Substance Registry System: Benzenemethanamine, N-(phenylmethyl)-N-2-propenyl-(22014-91-1)

Safety Data

• Hazardous Substances Data: 22014-91-1(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 107-11-9 1-amino-2-propene 
• 17455-13-9 18-crown-6 ether 
• 72654-43-4 n-propylammonium N-n-propylcarbamate 
• 169137-89-7 S-(prop-2-enyl)-S-phenyl-N-(p-tolylsulfonyl) sulfoximide 
• 103-49-1 dibenzylamine 
• 107-18-6 allyl alcohol 
• 103-67-3 benzyl-methyl-amine 
• 100-46-9 benzylamine 
• 591-87-7 Allyl acetate 
• 463-49-0 1,2-propanediene 
• 107-05-1 3-chloroprop-1-ene 
• 610299-80-4 Dibenzyl-carbamic acid allyl ester 
• 82813-00-1 2-allyl-2H-benzo[d][1,2,3]triazole 

Downstream Products

• 103-49-1 dibenzylamine 
• 2451-91-4 N,N-dibenzylcyanamide 
• 331959-06-9 2-(3,3-Dibenzylaminopropyl)-1,3,2-benzodioxaborole 
• 1043521-88-5 4-(dibenzylamino)-2-buten-1-ol 
• 1344667-71-5 2-allyl-6-methylbenzoic acid 
• 74914-74-2 dibenzylammonium trifluoroacetate salt 
• 88381-98-0 N-(1-phenyl-3-butenyl)benzylamine 
• 22014-89-7 N,N-dibenzyl-N-(n-propyl)amine 
• 94-66-6 2-allylcyclohexan-1-one 
• 180727-73-5 (C₄H₉)3SnCH₂CH₂CH₂N(CH₂C₆H₅)2 

Relevant articles and documents

Palladium-Catalyzed Reaction of N-Allylbenzotriazoles with Amines: A Novel Method for the Preparation of Allylamines

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Palladium(0) catalysed allylation reactions with racemic and enantiomerically pure allylic sulfoximines

Stabilised carbon and nitrogen nucleophiles can be efficiently allylated in a regioselective manner using allylic sulfoximines and palladium(0) catalysis.

Dehydrative Allylation of Amine with Allyl Alcohol by Titanium Oxide Supported Molybdenum Oxide Catalyst

The dehydrative allylation from allyl alcohol with amines to generate various allyl amines by MoO 3 /TiO 2 solid catalyst is described. The catalyst can be reused at least three times without a decrease of activity.

A Simple, Broad-Scope Nickel(0) Precatalyst System for the Direct Amination of Allyl Alcohols

The preparation of allylic amines is traditionally accomplished by reactions of amines with reactive electrophiles, such as allylic halides, sulfonates, or oxyphosphonium species; such methods involve hazardous reagents, generate stoichiometric waste streams, and often suffer from side reactions (such as overalkylation). We report here the first broad-scope nickel-catalysed direct amination of allyl alcohols: An inexpensive NiII/Zn couple enables the allylation of primary, secondary, and electron-deficient amines without the need for glove-box techniques. Under mild conditions, primary and secondary aliphatic amines react smoothly with a range of allyl alcohols, giving secondary and tertiary amines efficiently. This “totally catalytic” method can also be applied to electron-deficient nitrogen nucleophiles; the practicality of the process was demonstrated in an efficient, gram-scale preparation of the calcium antagonist drug substance flunarizine (Sibelium).