220156-99-0Relevant articles and documents
Folic acid targeting porphin photosensitizer coupled by different connecting chains and synthesis and application of folic acid targeting porphin photosensitizer
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Paragraph 0131; 0134-0135, (2020/12/15)
The invention relates to a folic acid targeting porphin photosensitizer coupled by different connecting chains and synthesis and application thereof, and discloses a photosensitizer as shown in a general formula (I), a preparation method of the photosensitizer and an application of the photosensitizer in tumor photodynamic therapy and tumor imaging diagnosis. In the photosensitizer, folic acid, which is a tumor-targeting ligand, is linked to a porphin-type photosensitive moiety via different chain lengths of linking moieties optionally having an acidic amino acid fragment. A-Lys-(L)m-(B)o-C(I)is shown in the specification.
Multivalent Siderophore–DOTAM Conjugates as Theranostics for Imaging and Treatment of Bacterial Infections
Ferreira, Kevin,Hu, Hai-Yu,Fetz, Verena,Prochnow, Hans,Rais, Bushra,Müller, Peter P.,Br?nstrup, Mark
supporting information, p. 8272 - 8276 (2017/06/30)
There is a strong need to better diagnose infections at deep body sites through noninvasive molecular imaging methods. Herein, we describe the synthesis and characterization of probes based on siderophore conjugates with catechol moieties and a central DO
TAGGABLE HETEROAROMATIC DRUGS AND CONJUGATES THEREOF
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Paragraph 0093; 00120, (2017/01/02)
The present invention provides heteroarene-based drag derivatives having a "clickable" ketone group, as well as conjugates of said drug derivatives with targeting moieties capable of binding to extracellular antigens; and pharmaceutical compositions compr