22046-72-6

Basic information

• Product Name: Ethanimidamide, N-(benzoyloxy)-
• Synonyms: O-Benzoyl-acetamidoxim
• CAS NO: 22046-72-6
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.191
• Mol File: 22046-72-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanimidamide, N-(benzoyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanimidamide, N-(benzoyloxy)-(22046-72-6)
• EPA Substance Registry System: Ethanimidamide, N-(benzoyloxy)-(22046-72-6)

Safety Data

• Hazardous Substances Data: 22046-72-6(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 75-05-8 acetonitrile 
• 118493-85-9 acetamide oxime 

Downstream Products

• 1199-00-4 3-methyl-5-phenyl-[1,2,4]oxadiazole 

Relevant articles and documents

Formation and Thermal Reaction of O-(N-Acetylbenzimidoyl)benzamidoxime: Comparison with the Formation of 3,5-Disubstituted 1,2,4-Oxadiazoles from O-Acetylarylamidoximes and O-Aroylacetamidoximes

Salts of O-(benzimidoyl)benzamidoxime have been obtained by the action of N-chloro- or N-bromo-succinimide, or the halogens, on benzamidoxime.Acetylation of the free base gave the title compound, which underwent a thermal cyclisation, with loss of acetamide, to give 3,5-diphenyl-1,2,4-oxadiazole.The mechanism of the reaction, in diphenyl ether, closely paralleled the thermal cyclisation of O-acetylarylamidoximes and O-aroylacetamidoximes, and is thought to involve a polar cyclisation step followed by rate-determining proton transfer. 13C N.m.r. spectra for 32 oxime, amidoxime, O-acetylamidoxime, 5-methyl-1,2,4-oxadiazol-3-yl, and 3-methyl-1,2,4-oxadiazol-5-yl groups on the phenyl ring are calculated.