22054-16-6Relevant articles and documents
Selective hydroboration of alkenes and alkynes in the presence of aldehydes and ketones
Kabalka, George W.,Yu, Su,Li, Nan-Sheng
, p. 800 - 805 (1998)
The reactions of terminal alkenes in the presence of ketones or aldehydes with a variety of borane reagents have been investigated. It was found that the selective hydroboration of a terminal alkene in the presence of a ketone or an aldehyde is most efficient when dicyclohexylborane is used as the hydroborating agent. The hydroboration of olefinic ketones and olefinic aldehydes with dicyclohexylborane generates the corresponding hydroxyaldehydes and hydroxyketones in good yields after oxidation with sodium perborate. The hydroboration of alkynyl ketones and alkynyl aldehydes with dicyclohexylborane yields the corresponding olefinic carbonyl compounds after protonation, or dicarbonyl compounds after oxidation.
Bidentate ligands by self-assembly through hydrogen bonding: A general room temperature/ambient pressure regioselective hydroformylation of terminal alkenes
Seiche, Wolfgang,Schuschkowski, Alexander,Breit, Bernhard
, p. 1488 - 1494 (2007/10/03)
The 6-DPPon (1)/rhodium catalyst allows for the first time a room temperature/ambient pressure regioselective hydroformylation of terminal alkenes with low catalyst loadings in good activity. The generality of this catalyst under these conditions was demonstrated for a wide range of structurally diverse alkenes equipped with many important functional groups. Thus, this practical and highly selective hydroformylation protocol, which omits the need for special pressure equipment, should find wide application in organic synthesis.
