220586-53-8

Basic information

• Product Name: diethyl (S_s,2R,3R)-(+)-N-(p-toluenesulfinyl)-3-phenylaziridine-2-phosphonate
• Synonyms: diethyl (S_s,2R,3R)-(+)-N-(p-toluenesulfinyl)-3-phenylaziridine-2-phosphonate
• CAS NO: 220586-53-8
• Molecular Weight: 393.444
• Mol File: 220586-53-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: diethyl (S_s,2R,3R)-(+)-N-(p-toluenesulfinyl)-3-phenylaziridine-2-phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl (S_s,2R,3R)-(+)-N-(p-toluenesulfinyl)-3-phenylaziridine-2-phosphonate(220586-53-8)
• EPA Substance Registry System: diethyl (S_s,2R,3R)-(+)-N-(p-toluenesulfinyl)-3-phenylaziridine-2-phosphonate(220586-53-8)

Safety Data

• Hazardous Substances Data: 220586-53-8(Hazardous Substances Data)

Upstream product

• 350479-90-2 (S,E)-N-benzylidene-4-methylbenzenesulfinamide 
• 3167-63-3 diethyl chloromethylphosphonate 
• 220586-51-6 diethyl (S_s,1R,2R)-1-chloro-2-phenyl-2-(p-toluenesulfinamido)ethylphosphonate 
• 10419-77-9 diethyl iodomethanephosphonate 

Downstream Products

• 220586-55-0 diethyl (2R,3R)-(+)-3-phenylaziridine-2-phosphonate 
• 118867-00-8 (R)-(1-Amino-2-phenylethyl)phosphonsaeure-diethylester 

Relevant articles and documents

Asymmetric synthesis of aziridine 2-phosphonates from enantiopure sulfinimines (N-sulfinyl imines). Synthesis of α-amino phosphonates

An aza-Darzens reaction, involving the addition of chloromethylphosphonate anions to enantiopure sulfinimines, has been developed for the asymmetric synthesis of aziridine 2-phosphonates. Best results involve cyclization of the syn and anti diastereomeric