220630-49-9

Basic information

• Product Name: Tris(2-azido-5-chlorobenzyl)amine N-oxide
• Synonyms: Tris(2-azido-5-chlorobenzyl)amine N-oxide
• CAS NO: 220630-49-9
• Molecular Weight: 529.776
• Mol File: 220630-49-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Tris(2-azido-5-chlorobenzyl)amine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Tris(2-azido-5-chlorobenzyl)amine N-oxide(220630-49-9)
• EPA Substance Registry System: Tris(2-azido-5-chlorobenzyl)amine N-oxide(220630-49-9)

Safety Data

• Hazardous Substances Data: 220630-49-9(Hazardous Substances Data)

Upstream product

• 220630-32-0 (2-azido-5-chlorophenyl)methanol 
• 220630-39-7 Bis-(2-azido-5-chloro-benzyl)-amine 
• 220630-35-3 2-azido-5-chlorobenzyl iodide 
• 220630-33-1 2-azido-5-chlorobenzyl chloride 
• 37585-25-4 2-amino-5-chlorobenzyl alcohol 
• 220630-40-0 Tris-(2-azido-5-chloro-benzyl)-amine 

Relevant articles and documents

Tripod-tripod coupling of triazides with triphosphanes. The synthesis, characterization, and stability in solution of new cage compounds: Chiral macrobicyclic triphosphazides

Several examples of a new type of cage compound, chiral macrobicyclic triphosphazides 15, have been prepared by tripod-tripod coupling of tris(2- azidobenzyl)amines with 1,1,1-tris[(diphenylphosphino)methyl] ethane (triphos). The structure determination of C3 or pseudo-C3-symmetric compounds 15 revealed their propellerlike topology, which accounted for their chirality, the rare Z configuration of the three phosphazide units, and a new conformation of the triphos fragment. Compounds 15 decomposed in solution with a phosphane arm-off mechanism, to give rise to complex mixtures instead of the expected tri-λ5-phosphazenes. The stability of 15 in solution was enhanced by the quaternization of the bridgehead nitrogen atom in the form of an N-oxide. Substituents either in the ortho position to the N termini of the phosphazide units or on the benzylic carbon atoms contributed to a decrease in the stability of macrobicycles 15, and in some cases even prevented their preparation.