220654-32-0

Basic information

• Product Name: C₈H₁₅NO₃S
• CAS NO: 220654-32-0
• Molecular Weight: 205.278
• Mol File: 220654-32-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₈H₁₅NO₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₈H₁₅NO₃S(220654-32-0)
• EPA Substance Registry System: C₈H₁₅NO₃S(220654-32-0)

Safety Data

• Hazardous Substances Data: 220654-32-0(Hazardous Substances Data)

Upstream product

• 6168-83-8 (S)-3-Hydroxybutanoic Acid 
• 1190-73-4 2-(acetylamino)ethanethiol 

Relevant articles and documents

Seven-enzyme in vitro cascade to (3R)-3-hydroxybutyryl-CoA

Economical and environmentally-friendly routes to convert feedstock chemicals like acetate into valuable chiral products such as (R)-3-hydroxybutyrate are in demand. Here, seven enzymes (CoaA, CoaD, CoaE, ACS, BktB, PhaB, and GDH) are employed in a one-pot, in vitro, biocatalytic synthesis of (3R)-3-hydroxybutyryl-CoA, which was readily isolated. This platform generates not only chiral diketide building blocks but also desirable CoA derivatives.

Enediyne polyketide synthases stereoselectively reduce the β-ketoacyl intermediates to β- D -hydroxyacyl intermediates in enediyne core biosynthesis

PKSE biosynthesizes an enediyne core precursor from decarboxylative condensation of eight malonyl-CoAs. The KR domain of PKSE is responsible for iterative β-ketoreduction in each round of polyketide chain elongation. KRs from selected PKSEs were investiga