22072-50-0

Basic information

• Product Name: 1-[4-(methoxymethyl)phenyl]ethan-1-one
• Synonyms: 1-[4-(methoxymethyl)phenyl]ethan-1-one;1-[4-(Methoxymethyl)phenyl]ethanone;4'-(Methoxymethyl)acetophenone;Einecs 244-767-1
• CAS NO: 22072-50-0
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.20108
• EINECS: 244-767-1
• Mol File: 22072-50-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 251.7°Cat760mmHg
• Flash Point: 103.8°C
• Appearance: /
• Density: 1.025g/cm³
• Vapor Pressure: 0.0201mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: 1-[4-(methoxymethyl)phenyl]ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(methoxymethyl)phenyl]ethan-1-one(22072-50-0)
• EPA Substance Registry System: 1-[4-(methoxymethyl)phenyl]ethan-1-one(22072-50-0)

Safety Data

• Hazardous Substances Data: 22072-50-0(Hazardous Substances Data)

Usage

Chemical Structure

C10H12O2

Type of Compound

Organic compound

Functional Group

Ketone

Structure

Benzene ring present
Methoxy group attached to the fourth carbon of the benzene ring
Methyl group attached to the first carbon of the ethanone chain

Usage

Fragrance ingredient
Used in manufacturing perfumes, soaps, and other scented products

Scent

Sweet, floral, and woody

Physical State

Clear, colorless liquid at room temperature

Solubility

Insoluble in water
Soluble in organic solvents such as ethanol and acetone

Safety Precautions

May cause irritation to skin, eyes, and respiratory system if exposed in high concentrations
Handle with caution

InChI:InChI=1/C10H12O2/c1-8(11)10-5-3-9(4-6-10)7-12-2/h3-6H,7H2,1-2H3

Upstream product

• 917-64-6 methyl magnesium iodide 
• 1515-85-1 4-(methoxymethyl)benzonitrile 
• 874-89-5 4-Cyanobenzyl alcohol 
• 1515-88-4 1-bromo-4-methoxymethylbenzene 
• 910251-11-5 potassium trifluoro(methoxymethyl)boranuide 
• 99-90-1 para-bromoacetophenone 
• 27490-32-0 tributyl(methoxymethyl)stannane 
• 78906-12-4 2-methyl-2-(4-hydoxymethylphenyl)-1,3-dioxolyn 
• 14490-45-0 4-(2-methyl-1,3-dioxolan-2-yl)benzaldehyde 

Downstream Products

• 66190-31-6 (+)-1-(4-methoxymethylphenyl)ethanol 
• 66190-31-6 (-)-1-(4-methoxymethylphenyl)ethanol 
• 137684-23-2 4-(methoxymethyl)phenylglyoxal 
• 1610345-74-8 2,2-dimethoxy-N-(1-(4-(methoxymethyl)phenyl)ethyl)ethanamine 
• 1610345-76-0 N-(2,2-dimethoxyethyl)-2,2,2-trifluoro-N-(1-(4-(methoxymethyl)phenyl)ethyl)ethanamine 

Relevant articles and documents

1,2,4-TRIAZINE-4-AMINE DERIVATIVES

According to the invention there is provided a compound of formula A1 which may be useful in the treatment of a condition or disorder ameliorated by the inhibition of the A1- A2b or, particularly, the A2a receptor wherein the compound of formula A1 has the structure, wherein, A represents Cy1 or HetA; Cy1 represents a 5- to 14-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one, two or three rings, which Cy1 group is optionally substituted by one or more R4a substituents; HetA represents a 5- to 14-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one, two or three rings and which HetA group is optionally substituted by one or more R4b substituents; B represents a Cy2 or HetB; Cy2 represents a 3- to 10-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one or two rings, which Cy2 group is optionally substituted by one or more R4c substituents; HetB represents a 3- to 10-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one or two rings and which HetB group is optionally substituted by one or more R4d substituents.

HYDROXYMETHYLBORON COMPOUNDS

The present invention provides compounds which are useful as safe substitutes for the organotin reagent used in coupling reaction for the oxymethylation of aromatic rings, such as alkoxymethylation or hydroxymethylation, with a palladium catalyst and which can dispense with chromatographic purification with silica gel in the production and are suitable for mass production; and compounds applicable even to the oxymethylation of aromatic ring substrates which do not permit coupling reaction by conventional technique or have low reactivity.