220996-81-6

Basic information

• Product Name: (4-Bromo-2-(trifluoromethoxy)phenyl)methanol
• Synonyms: (4-Bromo-2-(trifluoromethoxy)phenyl)methanol;4-Bromo-2-trifluoromethoxybenzylalcohol;2-trifluoroMethoxyl-4-broMobenzyl alcohol;(4-Bromo-2-(trifluoromethoxy);Benzenemethanol, 4-bromo-2-(trifluoromethoxy)-
• CAS NO: 220996-81-6
• Molecular Formula: C₈H₆BrF₃O₂
• Molecular Weight: 271.031
• Product Categories: Fluorine series
• Mol File: 220996-81-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 248°C at 760 mmHg
• Flash Point: 103.8°C
• Appearance: /
• Density: 1.695g/cm³
• Vapor Pressure: 0.0131mmHg at 25°C
• Refractive Index: 1.506
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (4-Bromo-2-(trifluoromethoxy)phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Bromo-2-(trifluoromethoxy)phenyl)methanol(220996-81-6)
• EPA Substance Registry System: (4-Bromo-2-(trifluoromethoxy)phenyl)methanol(220996-81-6)

Safety Data

• Hazardous Substances Data: 220996-81-6(Hazardous Substances Data)

Usage

General Description

(4-Bromo-2-(trifluoromethoxy)phenyl)methanol is a chemical compound with the molecular formula C8H6BrF3O2. It is a white to light yellow crystalline powder that is commonly used as a pharmaceutical intermediate in the synthesis of various pharmaceutical compounds. This chemical is known for its high purity, effectiveness, and stability, making it a valuable ingredient in the production of medications. Additionally, it is used in the research and development of new drug candidates due to its ability to modify the properties of various pharmaceutical substances. However, it is important to handle this compound with care, as it may pose health and environmental hazards if not properly managed.

InChI:InChI=1/C8H6BrF3O2/c9-6-2-1-5(4-13)7(3-6)14-8(10,11)12/h1-3,13H,4H2

Upstream product

• 220996-80-5 4-bromo-2-[(trifluoromethyl)oxy]benzaldehyde 

Downstream Products

• 220996-83-8 4-hydroxy-1-(tert-butyldimethyl-silyloxymethyl)-2-trifluoromethoxybenzene 
• 220996-86-1 4-(N-tert-butyloxycarbonyl-4-piperidinyloxy)-2-(trifluoromethoxy)benzyl bromide 
• 220996-85-0 4-(N-tert-butyloxycarbonyl-4-piperidinyloxy)-2-(trifluoromethoxy)benzyl alcohol 
• 220996-87-2 4-(N-tert-butyloxycarbonyl-4-piperidinyloxy)-2-(trifluoromethoxy)phenylacetonitrile 
• 220996-88-3 4-(N-tert-butyloxycarbonyl-4-piperidinyloxy)-2-(trifluoromethoxy)phenylacetic acid 
• 220996-84-9 4-(N-tert-butyloxycarbonyl-4-piperidinyloxy)-1-(tert-butyldimethylsilyloxy-methyl)-2-trifluoromethoxybenzene 
• 221285-22-9 1-(1-(2-trifluoromethoxy-4-(4-piperidinyloxy)phenylacetyl)-piperidin-4-yl)-4H-3,1-benzoxazin-2(1H)-one 
• 221286-44-8 4-(4-{2-oxo-2-[4-(2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin-1-yl]-ethyl}-3-trifluoromethoxy-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester 
• 947583-96-2 1-{4-bromo-2-[(trifluoromethyl)oxy]phenyl}methanamine 

Relevant articles and documents

NIPECOTIC ACID DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES

The present invention aims to provide a compound having an sEH-inhibiting activity and to provide a pharmaceutical having a therapeutic effect and a prophylactic effect on chronic renal disease and pulmonary hypertension based on the sEH-inhibiting action. The present invention provides nipecotic acid derivatives represented by the chemical formula below and pharmaceutically acceptable salts thereof.

Tocolytic oxytocin receptor antagonists

This invention relates to certain novel benzoxazinone compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor in mammals, especially humans. The ability of the compounds to relax uterine contractions in mammals also makes them useful for treating dysmenorrhea and stopping labor prior to cesarean delivery.

PIPERAZINE OXYTOCIN RECEPTOR ANTAGONISTS

This invention relates to certain novel piperazine compounds and derivatives thereof, their synthesis, and their use as oxytocin receptor antagonists. One application of these compounds is in the treatment of preterm labor in mammals, especially humans. The ability of the compounds to relax uterine contractions in mammals also makes them useful for treating dysmenorrhea and stopping labor prior to cesarean delivery.