221148-38-5 Usage
Description
(3-Fluoro-phenyl)-propynoic acid methyl ester is a chemical compound with the molecular formula C10H7FO2. It is a methyl ester derivative of propynoic acid, featuring a fluorine-substituted phenyl group. (3-Fluoro-phenyl)-propynoic acid methyl ester is known for its unique reactivity and physical properties due to the presence of the fluorine atom in the phenyl ring, making it a valuable building block in various chemical and pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
(3-Fluoro-phenyl)-propynoic acid methyl ester is used as an intermediate in the synthesis of various pharmaceuticals. Its unique reactivity and properties allow for the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, (3-Fluoro-phenyl)-propynoic acid methyl ester is utilized as a precursor in the production of agrochemicals. Its fluorinated structure can enhance the performance and selectivity of these compounds, leading to more effective pest control and crop protection.
Used in Dye Industry:
(3-Fluoro-phenyl)-propynoic acid methyl ester is used as a building block in the synthesis of dyes. The presence of the fluorine atom can impart specific color characteristics and improve the stability of the dyes, making them suitable for various applications, such as textiles and printing inks.
Used in Organic Chemical Reactions:
As a reagent, (3-Fluoro-phenyl)-propynoic acid methyl ester is employed in various organic chemical reactions. Its unique properties can be exploited to facilitate specific transformations, leading to the formation of new compounds with potential applications in various industries.
Used in Production of Other Chemical Compounds:
(3-Fluoro-phenyl)-propynoic acid methyl ester is also used in the production of other chemical compounds. Its versatility and reactivity make it a valuable component in the synthesis of a wide range of products, further expanding its applications across different sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 221148-38-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,1,4 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 221148-38:
(8*2)+(7*2)+(6*1)+(5*1)+(4*4)+(3*8)+(2*3)+(1*8)=95
95 % 10 = 5
So 221148-38-5 is a valid CAS Registry Number.
221148-38-5Relevant articles and documents
Asymmetric Transfer Hydrogenation of gem-Difluorocyclopropenyl Esters: Access to Enantioenriched gem-Difluorocyclopropanes
Archambeau, Alexis,Cossy, Janine,Meyer, Christophe,Pierre, Hugo,Yamani, Khalil
supporting information, p. 18505 - 18509 (2020/08/27)
Catalytic enantioselective access to disubstituted functionalized gem-difluorocyclopropanes, which are emerging fluorinated motifs of interest in medicinal chemistry, was achieved through asymmetric transfer hydrogenation of gem-difluorocyclopropenyl este
Rhodium(III)-Catalyzed Redox-Neutral Cascade [3 + 2] Annulation of N-Phenoxyacetamides with Propiolates via C-H Functionalization/Isomerization/Lactonization
Pan, Jin-Long,Chen, Chao,Hao, Yu,Liu, Chang,Bai, He-Yuan,Ding, Jun,Zhang, Shu-Yu,Wang, Li-Ren,Xie, Peipei,Xia, Yuanzhi
supporting information, p. 7131 - 7136 (2018/12/14)
A Rh(III)-catalyzed cascade [3 + 2] annulation of N-phenoxyacetamides with propiolates under mild conditions using the internal oxidative O-N bond as the directing group has been achieved. This catalytic system provides a regio- and stereoselective access to benzofuran-2(3H)-ones bearing exocyclic enamino motifs with exclusive Z configuration selectivity, acceptable to good yields and good functional group compatibility. Mechanistic investigations by experimental and density functional theory studies suggest that a consecutive process of C-H functionalization/isomerization/lactonization is likely to be involved in the reaction.
Palladium-Catalyzed Ylidyl-Carbonylation of Aryl Halides to Produce α-Acylphosphoranes
Guo, Xiaojun,Ma, Wei,Xue, Dong,Wang, Chao,Xiao, Jianliang
supporting information, p. 4824 - 4827 (2016/10/14)
An efficient synthesis of α-acylphosphoranes by palladium-catalyzed carbonylation of aryl iodides with carbon monoxide and stabilized phosphonium ylides has been developed. Featuring 44 examples, the protocol displayed a wide substrate scope under mild reaction conditions, showcasing its potential in synthetic organic chemistry.
