221218-91-3

Basic information

• Product Name: (4-trifluoromethyl-phenyl)-carbamic acid 2-(4-dibenzylsulfamoyl-phenyl)-2-oxo-ethyl ester
• CAS NO: 221218-91-3
• Molecular Weight: 582.6
• Mol File: 221218-91-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-trifluoromethyl-phenyl)-carbamic acid 2-(4-dibenzylsulfamoyl-phenyl)-2-oxo-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-trifluoromethyl-phenyl)-carbamic acid 2-(4-dibenzylsulfamoyl-phenyl)-2-oxo-ethyl ester(221218-91-3)
• EPA Substance Registry System: (4-trifluoromethyl-phenyl)-carbamic acid 2-(4-dibenzylsulfamoyl-phenyl)-2-oxo-ethyl ester(221218-91-3)

Safety Data

• Hazardous Substances Data: 221218-91-3(Hazardous Substances Data)

Upstream product

• 259227-07-1 N,N-dibenzyl-4-(2-bromoacetyl)benzenesulfonamide 
• 259227-06-0 4-acetyl-N,N-dibenzylbenzenesulfonamide 
• 61827-67-6 sodium 4-acetylbenzenesulfonate 
• 1788-10-9 4-Acetylbenzenesulfonyl chloride 
• 259227-08-2 N,N-dibenzyl-4-(2-hydroxyacetyl)benzenesulfonamide 
• 1548-13-6 p-trifluoromethyl-phenylisocyanate 

Downstream Products

• 259227-15-1 N,N-dibenzyl-4-[2-oxo-3-(4-trifluoromethylphenyl)-2,3-dihydrooxazol-4-yl]benzenesulfonamide 

Relevant articles and documents

Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors

A series of 3,4-diaryloxazolones were prepared and evaluated for their ability to inhibit cyclooxygenase-2 (COX-2). Extensive structure-activity relationship work was carried out within this series, and a number of potent and selective COX-2 inhibitors we