221349-56-0 Usage
Description
(3S,4S)-4-(4-(Benzyloxy)phenyl)-3-((S)-1,2-dihydroxyethyl)-1-(4-fluorophenyl)azetidin-2-one is a complex organic compound characterized by its unique molecular structure. It is a chiral molecule with specific stereochemistry at the 3rd and 4th carbon positions (3S,4S). The compound features a benzyloxy-phenyl group, a 1,2-dihydroxyethyl group, and a 4-fluorophenyl group attached to its azetidinone core. This structural diversity suggests potential applications in various fields, particularly in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
(3S,4S)-4-(4-(Benzyloxy)phenyl)-3-((S)-1,2-dihydroxyethyl)-1-(4-fluorophenyl)azetidin-2-one is used as a reactant in the synthesis of Sch 57939, a β-lactam-based cholesterol absorption inhibitor. This application is due to its structural compatibility with the target molecule, allowing for the creation of a compound with potential therapeutic benefits in managing cholesterol levels.
Used in Chemical Synthesis:
In the chemical synthesis industry, (3S,4S)-4-(4-(Benzyloxy)phenyl)-3-((S)-1,2-dihydroxyethyl)-1-(4-fluorophenyl)azetidin-2-one can be utilized as a building block or intermediate for the development of other complex organic molecules. Its unique functional groups and stereochemistry make it a valuable component in the synthesis of various pharmaceuticals, agrochemicals, or specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 221349-56-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,3,4 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 221349-56:
(8*2)+(7*2)+(6*1)+(5*3)+(4*4)+(3*9)+(2*5)+(1*6)=110
110 % 10 = 0
So 221349-56-0 is a valid CAS Registry Number.
221349-56-0Relevant articles and documents
A concise asymmetric synthesis of A β-lactam-based cholesterol absorption inhibitor
Wu, George Guangzhong
, p. 298 - 300 (2000)
A concise, four-step, asymmetric synthesis of β-lactam-based cholesterol absorption inhibitor, Sch 57939, was developed. The discovery of a one-step enantio- and diastereoselective synthesis of a trans-β-lactam provided easy access to the desired three chiral centers. A novel zinc phenoxide-promoted ether synthesis was reported for the completion of the side chain.