22184-23-2

Basic information

• Product Name: Benzenemethanol, 2,5-dimethyl-, acetate
• CAS NO: 22184-23-2
• Molecular Formula: C11H14O2
• Molecular Weight: 178.231
• Mol File: 22184-23-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2,5-dimethyl-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2,5-dimethyl-, acetate(22184-23-2)
• EPA Substance Registry System: Benzenemethanol, 2,5-dimethyl-, acetate(22184-23-2)

Safety Data

• Hazardous Substances Data: 22184-23-2(Hazardous Substances Data)

Upstream product

• 106-42-3 para-xylene 
• 64-19-7 acetic acid 
• 53957-33-8 2,5-dimethylbenzyl alcohol 
• 75-36-5 acetyl chloride 
• 824-45-3 2,5-dimethylbenzyl chloride 
• 127-08-2 potassium acetate 

Downstream Products

• 1310458-49-1 2,5-bis(bromomethyl)benzyl acetate 
• 188111-48-0 5-(bromomethyl)-1,3-dihydroisobenzofuran 
• 89424-84-0 5-hydroxymethyl-1,3-dihydroisobenzofuran 
• 1187196-40-2 5-(3,5-dichlorophenyl)-3-(1,3-dihydro-2-benzofuran-5-yl)-5-(trifluoromethyl)-4,5-dihydroisoxazole 
• 89424-83-9 1,3-dihydroisobenzofuran-5-carbaldehyde 
• 53957-33-8 2,5-dimethylbenzyl alcohol 

Relevant articles and documents

Condensation reactions of planar chiral tricarbonyl-chromium-complexed benzylic alcohols and acetates with reactive arenes

The condensation reaction of planar chiral 2- and 2,5-substituted tricarbonyl-chromium complexed benzylic alcohols and acetates with reactive arenes (durene, anisole, 1,3-dimethoxybenzene, diphenyl ether) is reported. The reactions were performed in both racemic and enantiomeric versions, optically pure and S-(-)-[2-methoxybenzyl alcohol]-tricarbonyl-chromium being prepared by LiAlH4 reduction of diastereomeric, t.l.c. separated, (-)-menthyl esters of [2-methoxybenzoic acis]-tricarbonyl-chromium. The condensation of the difunctional complex [1,4-diacetoxymethylene-2,5-dimethoxybenzene]-tricarbonyl- chromium with an excess of anisole proved the same reactivity at both reactive benzylic sites thus serving as a model for possible polycondensation process. Corresponding optically pure difunctional starting complexes were obtained by t.l.c. separation of diasteromeric diesters with R-(-)-lactic or S-(-)-mandelic acids.

Use of Tellurium(IV) and Tellurium(VI) as Oxidants in Organic Synthesis

The oxidizing properties of TeO2, Te(OH)6, and TeO3 in acetic acid solution containing LiBr have been explored.It was found that certain aromatic compounds were acetoxymethylated by the action of TeO2 or, when especially activated, converted into diarylmethane derivatives.Te(OH)6 and TeO3, in contrast, mainly effected side-chain acetoxylation, as was also the case with SeO2.In the acetoxymethylation reaction TeO2 apparently slowly oxidized the solvent, HOAc, to a reactive species of some kind, e.g., acetoxycarbene, which attacked the aromatic compound.In the side-chain acetoxylations, Te(VI) oxidized bromide ions to Br2, which caused benzylic bromination.The solvolysis of benzylic bromides to acetates was significantly enhanced by the presence of Te(IV) species.Both TeO2 and TeO3 effected more conventional oxidations like the transformation of deoxybenzil to benzil.Benzoin acetate is a probable intermediate in this oxidation.