221887-91-8Relevant articles and documents
Catalytic enantioselective alkylation of substituted dioxanone enol ethers: ready access to C(α)-tetrasubstituted hydroxyketones, acids,and esters
Seto, Masaki,Roizen, Jennifer L.,Stoltz, Brian M.
, p. 6873 - 6876 (2008)
(Chemical Equation Presented) Adaptive Alkylation: Palladium-catalyzed asymmetric alkylation enables access to fully substituted enantioenriched oxygenated stereocenters, which can be transformed easily to α-hydroxyketones, esters, and acids, providing a catalytic, enantioselective synthesis for natural products.