221903-19-1

Basic information

• Product Name: acetic acid 3-(2-formylamino-phenyl)-prop-2-ynyl ester
• Synonyms: acetic acid 3-(2-formylamino-phenyl)-prop-2-ynyl ester
• CAS NO: 221903-19-1
• Molecular Weight: 217.224
• Mol File: 221903-19-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: acetic acid 3-(2-formylamino-phenyl)-prop-2-ynyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: acetic acid 3-(2-formylamino-phenyl)-prop-2-ynyl ester(221903-19-1)
• EPA Substance Registry System: acetic acid 3-(2-formylamino-phenyl)-prop-2-ynyl ester(221903-19-1)

Safety Data

• Hazardous Substances Data: 221903-19-1(Hazardous Substances Data)

Upstream product

• 10113-39-0 N-formyl-2-iodoaniline 
• 108-24-7 acetic anhydride 
• 606146-01-4 2-(3-hydroxy-1-propynyl)formanilide 

Downstream Products

• 221903-20-4 Acetic acid (Z)-3-(2-formylamino-phenyl)-allyl ester 
• 221903-21-5 Acetic acid (Z)-3-(2-isocyano-phenyl)-allyl ester 
• 221903-28-2 2-(3-{2-[(2,4-dinitro-benzenesulfonyl)-(4-formyl-hexyl)-amino]-ethyl}-1H-indol-2-yl)-acrylic acid methyl ester 
• 221903-34-0 2-(3-{2-[(2,4-dinitro-benzenesulfonyl)-(4-ethyl-5-hydroxy-tetrahydro-furan-2-ylmethyl)-amino]-ethyl}-1H-indol-2-yl)-acrylic acid methyl ester 
• 221903-33-9 3-{2-[(2,4-dinitro-benzenesulfonyl)-(4-ethyl-2,3-dihydro-furan-2-ylmethyl)-amino]-ethyl}-2-(1-methoxycarbonyl-vinyl)-indole-1-carboxylic acid tert-butyl ester 
• 221903-27-1 3-{2-[(4-dimethoxymethyl-hexyl)-(2,4-dinitro-benzenesulfonyl)-amino]-ethyl}-2-(1-methoxycarbonyl-vinyl)-indole-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

Efficient total syntheses of (±)-vincadifformine and (-)-tabersonine

Stereocontrolled biomimetic total syntheses of the title compounds are described. Our syntheses feature a highly efficient preparation of the key intermediate 11 using our novel indole synthesis methodology. A novel amine protecting protocol by means of 2,4-dinitrobenzenesulfonamides has been developed to ensure the formation of the elusive secodine (3) as well as secodine-type intermediate (4) under very mild conditions.