22255-40-9 Usage
Description
LOGANIC ACID is an iridoid glycoside derived from C. mas, exhibiting a range of biological activities such as antidiabetic, antiadipogenic, anti-atherosclerotic, and anti-inflammatory properties. It is a cyclopentapyran with a unique structure, featuring beta-D-glucosyloxy, hydroxy, and methyl groups at specific positions.
Uses
Used in Pharmaceutical Industry:
LOGANIC ACID is used as a therapeutic agent for various health conditions due to its diverse biological activities. It aids in the treatment of diabetes by stimulating glucagon-like peptide-1 (GLP-1) secretion and inhibiting adipocyte differentiation. Additionally, it serves as an anti-atherosclerotic agent, reducing the plasma atherogenic index and cardiac risk ratio in a rabbit model of atherosclerosis induced by a cholesterol-rich diet.
Used in Anti-Inflammatory Applications:
LOGANIC ACID is used as an anti-inflammatory agent, as it helps decrease the levels of IL-6, TNF-α, and oxidized LDL (oxLDL) in the plasma, contributing to the reduction of inflammation in the body.
Used in Nutritional Supplements:
Given its antidiabetic and antiadipogenic properties, LOGANIC ACID can be used as an ingredient in nutritional supplements aimed at promoting healthy blood sugar levels and preventing obesity.
Used in Research and Development:
LOGANIC ACID's diverse biological activities make it a valuable compound for research and development in the fields of pharmacology, nutrition, and medicine, as it can potentially lead to the discovery of new treatments for various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 22255-40-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,5 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22255-40:
(7*2)+(6*2)+(5*2)+(4*5)+(3*5)+(2*4)+(1*0)=79
79 % 10 = 9
So 22255-40-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H24O10/c1-5-8(18)2-6-7(14(22)23)4-24-15(10(5)6)26-16-13(21)12(20)11(19)9(3-17)25-16/h4-6,8-13,15-21H,2-3H2,1H3,(H,22,23)
22255-40-9Relevant articles and documents
Algidisides I and II, New Iridoid Glycosides from Gentiana algida
Olennikov,Chirikova
, (2016)
Two new iridoid glycosides, algidiside I [2′-(2′′,3′′-dihydroxybenzoyl)loganic acid] (1) and algidiside II [6′-(2′′,3′′-dihydroxybenzoyl)loganic acid] (2), and 14 known iridoids including for the first time from the aerial part of Gentiana algida Pall. 2′
Iridoid glucosides from Picconia excelsa
Damtoft, Soren,Franzyk, Henrik,Jensen, Soren Rosendal
, p. 743 - 750 (1997)
An investigation of the iridoids of Picconia excelsa from Tenerife provided 17 iridoid glucosides together with verbascoside. Major constituents (> 0.5%) were loganin, ketologanin, oleoacteoside and the new picconioside I- a bisiridoid consisting of loganin esterified with deoxyloganin. Minor constituents were secoxyloganin, 8-epi-kingiside, oleoside 11-methyl ester, excelsioside, ligstroside and loganic acid together with the new compounds ketologanic acid, 6β-hydroxy-7-epi-loganin and picconiosides II-V, the latter four being esters of loganin and menthiafolic, foliamenthic, 6-(Z)- foliamenthic or 6,7-dihydrofoliamenthic acid. The structures were mainly elucidated by NMR spectroscopy.
7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures
Katano, Nobuyuki,Yamamoto, Hirobumi,Iio, Reiko,Inoue, Kenichiro
, p. 53 - 58 (2007/10/03)
The activity of 7-deoxyloganin 7-hydroxylase, an enzyme catalyzing the conversion of 7-deoxyloganin into loganin, was detected in a microsomal preparation from the cell suspension cultures of Lonicera japonica. It was dependent on NADPH and molecular oxyg
