22300-56-7 Usage
General Description
4-Methyl-2-phenyl-1,2,3-triazole-5-carboxylic acid is a specific compound belonging to the classification of chemicals known as triazoles. Triazoles are nitrogen-containing rings that are often used in pharmaceuticals and agrochemicals. The presence of both methyl and phenyl groups in 4-Methyl-2-phenyl-1,2,3-triazole-5-carboxylic acid indicate variations in the basic triazole structure, which can influence the properties and reactivity of the compound. This particular chemical may be involved in various chemical reactions and could be part of more complex chemical compounds. However, its specific uses or properties are not commonly highlighted in generalized chemical literature, suggesting that it is more likely to be used in specific, possibly specialized, chemical contexts.
Check Digit Verification of cas no
The CAS Registry Mumber 22300-56-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,3,0 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 22300-56:
(7*2)+(6*2)+(5*3)+(4*0)+(3*0)+(2*5)+(1*6)=57
57 % 10 = 7
So 22300-56-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H9N3O2/c1-7-9(10(14)15)12-13(11-7)8-5-3-2-4-6-8/h2-6H,1H3,(H,14,15)/p-1
22300-56-7Relevant articles and documents
Cu-Mediated Expeditious Annulation of Alkyl 3-Aminoacrylates with Aryldiazonium Salts: Access to Alkyl N2-Aryl 1,2,3-Triazole-carboxylates for Druglike Molecular Synthesis
Liu, Hao-Nan,Cao, Hao-Qiang,Cheung, Chi Wai,Ma, Jun-An
, p. 1396 - 1401 (2020/02/22)
Alkyl N-aryl 1,2,3-triazole-carboxylates are important molecules or intermediates in medicinal chemistry, but the synthesis of N2-aryl counterparts remains elusive. Herein, we describe a Cu-mediated annulation reaction of alkyl 3-aminoacrylates with aryldiazonium salts, both of which are readily available substrates. Furthermore, alkyl 2-aminoacrylates are also viable substrates. Diverse alkyl N2-aryl 1,2,3-triazole-carboxylates and their analogues can be rapidly prepared under mild conditions. Especially, this protocol allows one to access several druglike variants of carbonic anhydrase inhibitors and celecoxib.
Methylation of 3-Methyl- and 3-Phenyl-4-arylhydrazonoisoxazol-5-ones with Diazomethane
Singh, Shyam K.,Summers, Lindsay A.
, p. 933 - 939 (2007/10/02)
3-Methyl(or phenyl)-4-arylhydrazonoisoxazol-5-ones on methylation with diazomethane afford 3-methyl(or phenyl)-4-(N-methylarylhydrazono)isoxazol-5-ones and 3-methyl(or phenyl)-5-methoxy-4-arylhydrazonoisoxazoles.The latter compounds readily rearrange to 4