223382-92-1

Basic information

• Product Name: (2S,4S)-2-methyl-2-phenyl-1,3-dioxan-4-methanol
• CAS NO: 223382-92-1
• Molecular Weight: 208.257
• Mol File: 223382-92-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4S)-2-methyl-2-phenyl-1,3-dioxan-4-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-2-methyl-2-phenyl-1,3-dioxan-4-methanol(223382-92-1)
• EPA Substance Registry System: (2S,4S)-2-methyl-2-phenyl-1,3-dioxan-4-methanol(223382-92-1)

Safety Data

• Hazardous Substances Data: 223382-92-1(Hazardous Substances Data)

Upstream product

• 42890-76-6 (S)-1,2,4-butanetriol 
• 4316-35-2 acetophenone dimethyl acetal 
• 196861-66-2 (S)-2,2,9,9-tetramethyl-5-<(trimethylsilyl)oxy>-3,8-dioxa-2,9-disiladecane 

Relevant articles and documents

Towards the diastereoselective functionalization of non-racemic acetal derivatives of η6-arylcarbonyl complexes of tricarbonylchromium

(S)-Butane-1,2,4-triol (2) has been investigated as a potential chiral auxiliary for the formation of non-racemic acetals derived from η6-arylcarbonyl complexes of tricarbonylchromium. Predominantly the cis dioxan (5) was formed from benzaldehyde, leading to preparation of the η6-Cr(CO)3 complex (16), and of the derived complexes (23) and (24). Lithiation-electrophile quenching of these complexes gave a mixture of products arising from ortho and benzylic functionalization. Reaction of acetophenone, or of the η6-Cr(CO)3 complexes (45) or (46), with either the triol (2) or its tris(silyl) ether (15) under conditions of kinetic or thermodynamic control gave an inseparable mixture of acetals.