22345-38-6

Basic information

• Product Name: 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol
• Synonyms: 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol
• CAS NO: 22345-38-6
• Molecular Formula: C₁₃H₁₂OS
• Molecular Weight: 216.29878
• Mol File: 22345-38-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol(22345-38-6)
• EPA Substance Registry System: 9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ol(22345-38-6)

Safety Data

• Hazardous Substances Data: 22345-38-6(Hazardous Substances Data)

Upstream product

• 1622-55-5 9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophen-4-one 
• 32358-88-6 4-Bromotetrahydrothiopyran 

Downstream Products

• 91164-65-7 1,6,7,11b-tetrahydro-3-phenylbenzo<1,2>cyclohepta<3,4,5-hi>thieno<3,4-c>pyridine 
• 81885-62-3 N-(9,10-dihydro-4H-benzo<4,5>cyclohepta<1,2-b>thiophene-4-yl-methyl)benzamide 

Relevant articles and documents

TRICYCLIC HETEROCYCLES AS ANTICANCER AGENTS

Tricyclic chemical modulators of FOXO transcription factor proteins are disclosed. The compounds are useful to treat cancer, age-onset proteotoxicity, stress-induced depression, inflammation, and acne. The compounds are of the following and similar genera

HETEROCYCLIC ETHERS DERIVED FROM 6,11-DIHYDRODIBENZOTHIEPIN-11-OLS AND 4,9-DIHYDROTHIENO-2-BENZOTHIEPIN-4-OL; A NEW SERIES OF POTENTIAL ANTIDEPRESSANTS AND ANTIHISTAMINE AGENTS

Reactions of 11-chloro-6,11-dihydrodibenzothiepin and methanesulfonates of 6,11-dihydrodibenzothiepin-11-ol (I), its 2-methyl derivative II and 4,9-dihydrothieno-2-benzothiepin-4-ol (III) with 1-methylpiperidin-4-ol, 1-methylperhydroazepin-4-ol (XIX), and tropine gave the ethers V-X.Their methanesulfonates were pharmacologically tested and showed antireserpine, anticataleptic, and antihistamine activities of various degree.The most active compounds were the ethers V and VI.