22349-44-6

Basic information

• Product Name: C₁₇H₂₀OSi
• Synonyms: C₁₇H₂₀OSi
• CAS NO: 22349-44-6
• Molecular Weight: 268.431
• Mol File: 22349-44-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₂₀OSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₂₀OSi(22349-44-6)
• EPA Substance Registry System: C₁₇H₂₀OSi(22349-44-6)

Safety Data

• Hazardous Substances Data: 22349-44-6(Hazardous Substances Data)

Upstream product

• 1012-12-0 4-(trimethylsiloxy)benzaldehyde 
• 1449-46-3 benzyltriphenylphosphonium bromide 

Downstream Products

• 6554-98-9 trans-4-Hydroxystilbene 
• 3839-46-1 (Z)-1-(4-hydroxyphenyl)-2-phenylethene 

Relevant articles and documents

Syntheses of polyfunctionalized resveratrol derivatives using Wittig and Heck protocols

Improved protocols for Wittig reaction and palladium-catalyzed Heck coupling give expedient access to a series of unprecedented polyfunctionalized artificial-resveratrol derivatives. In the modified Wittig protocol, trimethylsilyl was used as a highly valuable protective group of the phenolic functions of starting aromatic materials. A clean O-alkylation of hydroxylated stilbenes with ethylene carbonate was also conducted. Thus, Wittig reaction followed by hydroxyethylation take place one-pot with only carbon dioxide as waste. Additionally, a palladium-catalyzed Heck coupling strategy was developed by using ferrocenyl phosphane ligands, and multi-functionalized hydroxylated stilbenes were obtained without the need of any protection/deprotection sequence. Up to six functional groups are introduced by these procedures, which limit the number of reactions steps, the waste toxicity, and the use of costly reagents.