223651-67-0

Basic information

• Product Name: [2-[[N-[2-(Dibutylamino)ethyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide
• Synonyms: [2-[[N-[2-(Dibutylamino)ethyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide
• CAS NO: 223651-67-0
• Molecular Weight: 601.957
• Mol File: 223651-67-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-[[N-[2-(Dibutylamino)ethyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide(CAS DataBase Reference)
• NIST Chemistry Reference: [2-[[N-[2-(Dibutylamino)ethyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide(223651-67-0)
• EPA Substance Registry System: [2-[[N-[2-(Dibutylamino)ethyl]carbamoyloxy]methyl]phenyl]-N-octadecylformamide(223651-67-0)

Safety Data

• Hazardous Substances Data: 223651-67-0(Hazardous Substances Data)

Upstream product

• 223651-41-0 [2-(hydroxymethyl)phenyl]-N-octadecylformamide 
• 3529-09-7 n,n-di-n-butylethylenediamine 
• 1885-14-9 phenyl chloroformate 

Relevant articles and documents

1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same

A 1,2-di-substituted benzene-carboxamide derivative or a salt thereof expressed by the following Formula (I); wherein each of A and B is R1 or -(CH2)n-NR2R3, wherein when A is R1, B is -(CH2)n-NR2R3 and when A is -(CH2)n-NR2R3, B is R1; Z is -O-, -OCO-, -OCONR6- or -NR6-; R1 is a hydrocarbon group of C10-30; R2 and R3 individually represent a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group, or together represent a heterocyclic ring having 3-7 members; when A is -(CH2)n-NR2R3, R2 may be a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group, and R3 and R5 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; when -Z-B is -OCONR6-(CH2)n-NR2R3 or -NR6-(CH2)n-NR2R3, R2 may be a hydrogen atom, a lower alkyl group, a phenyl group or a benzyl group, and R3 and R6 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; R4 is selected from the group consisting of a halogen atom, a lower alkyl group, a lower acyl group, a nitro group, a cyano group, a lower alkoxycarbonyl group, a carbamoyl group, a lower alkylcarbamoyl group, a lower alkylamino group, a lower acylamino group, a lower alkoxy group and a lower acyloxy group; R5 is a hydrogen atom, a lower alkyl group, a lower acyl group or a lower alkylcarbamoyl group, or when A is -(CH2)n-NR2R3, R5 and R3 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; R6 is a hydrogen atom, a lower alkyl group, a lower acyl group or a lower alkylcarbamoyl group, or when -Z-B is -OCONR6-(CH2)n-NR2R3 or -NR6-(CH2)n-NR2R3, R6 and R3 together may represent a heterocyclic ring of 6 or 7 members including two nitrogen atoms; l is an integer of 0-2; and n is an integer of 0-5. The 1,2-di-substituted benzene-carboxamide derivative or the salt thereof has excellent hair growth and regrowth promoting effects, which are useful for care, improvement or prevention of hair loss in mammals and, in particular, in humans.