223704-18-5Relevant articles and documents
Conformationally biased selective alkylation of trans-cyclohexane-1,2- bis(sulfonamide) assisted by solvent-tuned protecting groups: Applications to the synthesis of a large optically active polyazamacrocycle
Pena, Carmen,Alfonso, Ignacio,Gotor, Vicente
, p. 3887 - 3897 (2007/10/03)
The selective alkylation of (R,R)-cyclohexane-1,2-bis(sulfonamide) with trityl bromoalkyl ethers has been studied in detail. The major formation of either mono- or dialkylated compounds clearly depends on the right combination of protecting groups and the