2241-98-7

Basic information

• Product Name: 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE
• Synonyms: 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE;Naphthalen-2-ylmethylamine hydrochloride;Naphthalene-2-MethanaMine hydrochloride;Naphthalene-2-MethanaMine;2-aMinoMethylnaphthalene hydrochloride;Naphthalen-2-ylMethanaMine hydrochloride;2-NaphthaleneMethylaMine, HCl;NAPHTHALEN-2-YLMETHANAMINE HCL
• CAS NO: 2241-98-7
• Molecular Formula: C₁₁H₁₁N*ClH
• Molecular Weight: 193.67
• Mol File: 2241-98-7.mol
• Article Data: 15

Chemical Properties

• Melting Point: 268-270 °C
• Boiling Point: 333.2 °C at 760 mmHg
• Flash Point: 155.3 °C
• Appearance: /
• Vapor Pressure: 9.96E-05mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE(2241-98-7)
• EPA Substance Registry System: 2-NAPHTHALENEMETHYLAMINE HYDROCHLORIDE(2241-98-7)

Safety Data

• Hazardous Substances Data: 2241-98-7(Hazardous Substances Data)

Usage

General Description

2-Naphthalenemethylamine hydrochloride is a chemical compound with the molecular formula C11H11ClN. It is also known by its IUPAC name, 2-aminobenzylbenzene hydrochloride. This substance is mainly used in the field of chemistry, particularly in chemical research and analysis. As implied by its name, it contains hydrochloride, which suggests it can function as an acid in certain conditions. Detailed information about its physical properties, potential health risks, or protective measures isn't readily available, indicating that it's typically handled and studied by professionals in controlled environments. It is crucial to adhere to safety protocols when working with this substance to avoid any potential negative impact on health or the environment.

InChI:InChI=1/C11H11N.ClH/c12-8-9-5-6-10-3-1-2-4-11(10)7-9;/h1-7H,8,12H2;1H

Upstream product

• 2243-83-6 2-naphthaloyl chloride 
• 2243-82-5 2-naphthamide 
• 2018-90-8 naphthalen-2-ylmethylamine 
• 613-46-7 2-naphthalenecarbonitrile 

Downstream Products

• 1354483-28-5 (1R)-1-C-allyl-2,3,4-tri-O-benzyl-1-naphth-2-ylmethylamino-1-deoxy-D-xylitol 

Relevant articles and documents

Deoxygenative hydroboration of primary, secondary, and tertiary amides: Catalyst-free synthesis of various substituted amines

Transformation of relatively less reactive functional groups under catalyst-free conditions is an interesting aspect and requires a typical protocol. Herein, we report the synthesis of various primary, secondary, and tertiary amines through hydroboration of amides using pinacolborane under catalyst-free and solvent-free conditions. The deoxygenative hydroboration of primary and secondary amides proceeded with excellent conversions. The comparatively less reactive tertiary amides were also converted to the corresponding N,N-diamines in moderate yields under catalyst-free conditions, although alcohols were obtained as a minor product.

Method for preparing amine compound by reducing amide compound

The invention relates to a method for preparing an amine compound by reducing an amide compound, which comprises the following steps: in a protective atmosphere, mixing the amide compound or cyclic amide, a zirconium metal catalyst and pinacol borane, carrying out amide reduction reaction at room temperature, and carrying out aftertreatment by using an ether solution of hydrogen chloride after 12-48 hours to obtain an amine hydrochloride compound. The method is simple to operate, low in cost, good in functional group tolerance and wide in substrate range.

Hydrosilylative reduction of primary amides to primary amines catalyzed by a terminal [Ni-OH] complex

A terminal [Ni-OH] complex1, supported by triflamide-functionalized NHC ligands, catalyzes the hydrosilylative reduction of a range of primary amides into primary amines in good to excellent yields under base-free conditions with key functional group tolerance. Catalyst1is also effective for the reduction of a variety of tertiary and secondary amides. In contrast to literature reports, the reactivity of1towards amide reduction follows an inverse trend,i.e., 1° amide > 3° amide > 2° amide. The reaction does not follow a usual dehydration pathway.