2243-30-3

Basic information

• Product Name: pentamethylaminobenzene
• Synonyms: pentamethylaminobenzene;pentamethylaniline;2,3,4,5,6-Pentamethylaniline
• CAS NO: 2243-30-3
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.26
• Mol File: 2243-30-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 152.5°C
• Boiling Point: 253.03°C (estimate)
• Appearance: /
• Density: 0.9137 (estimate)
• Refractive Index: 1.5115 (estimate)
• PKA: 4.98±0.10(Predicted)
• CAS DataBase Reference: pentamethylaminobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: pentamethylaminobenzene(2243-30-3)
• EPA Substance Registry System: pentamethylaminobenzene(2243-30-3)

Safety Data

• Hazardous Substances Data: 2243-30-3(Hazardous Substances Data)

Upstream product

• 98-04-4 phenyltrimethylammonium iodide 
• 13171-59-0 1-nitro-2,3,4,5,6-pentamethylbenzene 
• 7647-01-0 hydrogenchloride 
• 65594-36-7 1,2,3,4,5-pentamethyl-6-nitrosobenzene 
• 700-12-9 pentamethylbenzene, 
• 3853-91-6 2,3,4,5,6-pentamethyliodobenzene 
• 85518-76-9 3,5-dimethylphenylamine hydrochloride 
• 67-56-1 methanol 
• 35122-87-3 2,4,5,N,N-pentamethyl-aniline 
• 74-88-4 methyl iodide 

Downstream Products

• 5153-39-9 6-chloro-1,2,3,4,5-pentamethylbenzene 
• 1579250-30-8 1-((1S,2S)-2-cyclohexyloxyindan-1-yl)-3-pentamethylphenylimidazolinium hexafluorophosphate 
• 1579250-36-4 N-((1S,2S)-2-(2-cyclohexyloxy)-1-indanyl)-N′-(2,3,4,5,6-pentamethylphenyl)oxalamide 
• 1579250-28-4 1-((1S,2S)-2-methoxyindan-1-yl)-3-pentamethylphenylimidazoliniumHexafluorophosphate 
• 1579250-24-0 1-((1S,2S)-2-hydroxyindan-1-yl)-3-pentamethylphenylimidazolinium hexafluorophosphate 
• 1579250-33-1 N-(2,3,4,5,6-pentamethylphenyl)-N′-((1S,2S)-2-hydroxy-1-indanyl)oxalamide 
• 1579250-32-0 ethyl 2,3,4,5,6-pentamethylphenyloxamate 
• 914306-63-1 N-(2,3,4,5,6-pentamethylbenzene)-2-(4-fluorophenyl)imidazolidine 
• 914306-55-1 N-(2,3,4,5,6-pentamethylbenzene)-2-phenylimidazole 
• 105201-10-3 2-amino-2',3',4',5',6'-pentamethyldiphenylamine hydrochloride 
• 82757-40-2 1-(2,3,4,5,6-pentamethylphenyl)benzotriazole 
• 82757-36-6 2,3,4,5,6-pentamethyl-2'-nitrodiphenylamine 
• 132588-49-9 N-(1',1'-dimethylprop-2'-ynyl)-2,3,4,5,6-pentamethylaniline 
• 319-83-5 pentamethylfluorobenzene 

Relevant articles and documents

A Metal-Free Direct Arene C?H Amination

The synthesis of aryl amines via the formation of a C?N bond is an essential tool for the preparation of functional materials, active pharmaceutical ingredients and bioactive products. Usually, this chemical connection is only possible by transition metal-catalyzed reactions, photochemistry or electrochemistry. Here, we report a metal-free arene C?H amination using hydroxylamine derivatives under benign conditions. A charge transfer interaction between the aminating reagents TsONHR and the arene substrates enables the chemoselective amination of the arene, even in the presence of various functional groups. Oxygen was crucial for an effective conversion and its accelerating role for the electron transfer step was proven experimentally. In addition, this was rationalized by a theoretical study which indicated the involvement of a dioxygen-bridged complex with a “Sandwich-like” arrangement of the aromatic starting materials and the aminating agents at the dioxygen molecule. (Figure presented.).

IMPROVED STABILITY OLED MATERIALS AND DEVICES

Organic light emitting materials and devices comprising phosphorescent metal complexes comprising ligands comprising aryl or heteroaryl groups substituted at both ortho positions are described. An organic light emitting device, comprising: an anode; a hole transport layer; an organic emissive layer comprising an emissive layer host and an emissive dopant; an electron impeding layer; an electron transport layer; and a cathode disposed, in that order, over a substrate.

N-heteroaryl aryl-substituted thienyl-furyl-and pyrrolyl-sulfonamides and derviatives thereof that modulate the activity of endothelin

Thienyl-, furyl- and pyrrolyl-sulfonamides, formulations of pharmaceutically-acceptable salts thereof and methods for modulating or altering the activity of the endothelin family of peptides are provided. In particular, N-(isoxazolyl)thienylsulfonamides, N-(isoxazolyl)furylsulfonamides and N-(isoxazolyl)pyrrolylsulfonamides, formulations thereof and methods using these sulfonamides for inhibiting the binding of an endothelin peptide to an endothelin receptor by contacting the receptor with the sulfonamide are provided. Methods for treating endothelin-mediated disorders by administering effective amounts of one or more of these sulfonamides or prodrugs thereof that inhibit the activity of endothelin are also provided.