224635-17-0

Basic information

• Product Name: (R)-3-[(2-amino-acetyl)amino]-3-(4-{3-methoxy-4-[3-(2-methylphenyl)ureido]phenyl-acetylamino}phenyl)propanoic acid
• Synonyms: (R)-3-[(2-amino-acetyl)amino]-3-(4-{3-methoxy-4-[3-(2-methylphenyl)ureido]phenyl-acetylamino}phenyl)propanoic acid
• CAS NO: 224635-17-0
• Molecular Weight: 533.584
• Mol File: 224635-17-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-[(2-amino-acetyl)amino]-3-(4-{3-methoxy-4-[3-(2-methylphenyl)ureido]phenyl-acetylamino}phenyl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-[(2-amino-acetyl)amino]-3-(4-{3-methoxy-4-[3-(2-methylphenyl)ureido]phenyl-acetylamino}phenyl)propanoic acid(224635-17-0)
• EPA Substance Registry System: (R)-3-[(2-amino-acetyl)amino]-3-(4-{3-methoxy-4-[3-(2-methylphenyl)ureido]phenyl-acetylamino}phenyl)propanoic acid(224635-17-0)

Safety Data

• Hazardous Substances Data: 224635-17-0(Hazardous Substances Data)

Upstream product

• 4530-20-5 BOC-glycine 
• 224635-49-8 (R)-3-amino-3-(4-{3-methoxy-4-[3-(2-methylphenyl)ureido]phenylacetylamino}-phenyl)-propanoic acid methyl ester 
• 200731-31-3 HATU 

Relevant articles and documents

Substituted anilides

The invention is directed to physiologically active compounds of formula (I): wherein: R1is hydrogen, halogen, hydroxy, lower alkyl or lower alkoxy; X1, X2and X6independently represent N or CR10; and one of X3, X4and X5represents CR11and the others independently represents N or CR10; where R10is hydrogen, amino, halogen, hydroxy, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl, lower alkylsulphonyl, nitro or trifluoromethyl; and R11represents a group —L1—Ar1—L2—Y; and the corresponding N-oxides, and their prodrugs; and pharmaceutically acceptable salts and solvates of such compounds and their N-oxides and prodrugs. Such compounds have valuable pharmaceutical properties, in particular the ability to regulate the interaction of VCAM-1 and fibronectin with the integrin VLA-4 (α4β1).