22489-76-5

Basic information

• Product Name: 3-(4-methoxyphenyl)-2,2-dimethylpropanal
• CAS NO: 22489-76-5
• Molecular Weight: 192.258
• Mol File: 22489-76-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(4-methoxyphenyl)-2,2-dimethylpropanal(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-methoxyphenyl)-2,2-dimethylpropanal(22489-76-5)
• EPA Substance Registry System: 3-(4-methoxyphenyl)-2,2-dimethylpropanal(22489-76-5)

Safety Data

• Hazardous Substances Data: 22489-76-5(Hazardous Substances Data)

Upstream product

• 6651-34-9 2-methyl-1-(trimethylsilyloxy)-1-propene 
• 824-94-2 p-methoxybenzyl chloride 
• 78-84-2 isobutyraldehyde 
• 696-62-8 para-iodoanisole 
• 630-19-3 pivalaldehyde 
• 1775-74-2 N-(2,2-dimethylpropylidene)benzylamine 

Relevant articles and documents

Single operation palladium catalysed C(sp3)-H functionalisation of tertiary aldehydes: Investigations into transient imine directing groups

Simple amine and diamine derivatives can promote the palladium catalysed direct β-C-H arylation of aliphatic aldehydes via transient imine formation. Trifluoroacetate was shown to be crucial in promoting the reaction. Sub-stoichiometric quantities of simple N-tosylethylenediamine was shown to form a bidentate directing group with an imine linkage. Isolation of an unsymmetrical palladacycle has shown different potential binding modes of the secondary NTs coordinating group by single crystal X-ray diffraction analysis, suggestive of a hemilabile ligand.

Coupling reaction of alkyl chlorides with silyl enolates catalyzed by indium trihalide

Indium(III) halide catalyzed not only the coupling of alkyl chlorides with silyl enolates derived from esters, ketones, and aldehydes to give a variety of α-alkylated carbonyl compounds but also one-pot, three-component reactions of aldehyde enolate, alkyl chloride, and allylsilane or alkynylsilane.