225928-10-9

Basic information

• Product Name: methyl 4-(2-bromoethynyl)benzoate
• Synonyms: methyl 4-(2-bromoethynyl)benzoate;methyl 4-(bromoethynyl)benzoate;Methyl 4-(bromoethynyl)
• CAS NO: 225928-10-9
• Molecular Formula: C₁₀H₇BrO₂
• Molecular Weight: 239
• Mol File: 225928-10-9.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 303.5±44.0 °C(Predicted)
• Appearance: /
• Density: 1.53±0.1 g/cm3(Predicted)
• CAS DataBase Reference: methyl 4-(2-bromoethynyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-bromoethynyl)benzoate(225928-10-9)
• EPA Substance Registry System: methyl 4-(2-bromoethynyl)benzoate(225928-10-9)

Safety Data

• Hazardous Substances Data: 225928-10-9(Hazardous Substances Data)

Usage

General Description

Methyl 4-(2-bromoethynyl)benzoate is a chemical compound with the molecular formula C11H9BrO2. It is a pale yellow liquid with a distinct odor and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound is also utilized in the manufacturing of dyes and perfumes. Methyl 4-(2-bromoethynyl)benzoate is known for its high stability and low reactivity, making it a valuable building block in organic synthesis. It is important to handle this compound with care as it may cause skin and eye irritation upon contact, and it should be stored in a cool, dry place away from direct sunlight and heat sources.

Upstream product

• 253684-21-8 1,1-dibromo-2-(4-methoxycarbonylphenyl)ethene 
• 1571-08-0 methyl 4-formylbenzoate 
• 1616766-87-0 methyl 4-((triisopropylsilyl)ethynyl)benzoate 
• 619-42-1 4-methoxycarbonylphenyl bromide 
• 75867-41-3 4-trimethylsilanylethynyl-benzoic acid methyl ester 
• 3034-86-4 4-ethynylbenzoic acid methyl ester 
• 619-44-3 methyl 4-iodobenzoate 

Downstream Products

• 727992-64-5 methyl 4-((1H-benzo[d]imidazol-2-yl)methyl)benzoate 
• 116075-75-3 4,4’-(buta-1,3-diyne-1,4-diyl)dibenzoic acid 
• 1093193-97-5 4-(4-cyclopropylbuta-1,3-diyn-1-yl)benzoic acid 
• 1344700-32-8 1-(4-cyclopropylbuta-1,3-diyn-1-yl)-4-{[1-methoxy-3-(methylamino)-1,3-dioxopropan-2-yl](methyl)carbamoyl}benzene 
• 1344698-60-7 2-({[4-(4-cyclopropylbuta-1,3-diyn-1-yl)phenyl]carbonyl}(methyl)amino)-N-hydroxy-N'-methylpropanediamide 
• 1344700-30-6 4-(4-cyclopropylbuta-1,3-diyn-1-yl)benzoic acid methyl ester 
• 1519058-83-3 methyl 4-[(tetrahydrofuran-2-yl)ethynyl]benzoate 
• 1616766-74-5 4-[(1Z,3E)-1-chloro-5-methylhexa-1,3,5-trien-1-yl]benzoic acid 
• 1616766-80-3 C₃₀H₂₈Cl₂O₆ 
• 1616766-72-3 C₃₅H₃₂ClNO₇ 
• 1616766-81-4 C₃₇H₃₅ClO₈ 
• 1616766-82-5 C₄₅H₄₂ClNO₉ 
• 1616766-83-6 C₃₇H₃₆ClNO₆ 
• 1616766-84-7 C₃₇H₃₆ClNO₆ 

Relevant articles and documents

Copper-Catalyzed Perfluoroalkylation of Alkynyl Bromides and Terminal Alkynes

A copper-catalyzed one-pot perfluoroalkylation of alkynyl bromides and terminal alkynes has been disclosed, and the corresponding perfluoroalkylated alkynes could be attained in good to excellent yields. The new straightforward transformation shows high efficiency (0.01-0.5 mol % catalyst loading), broad substrate scope, and remarkable functional group tolerance and provides a facile approach for useful application in life and material sciences.

Multicolor Cocktail for Breast Cancer Multiplex Phenotype Targeting and Diagnosis Using Bioorthogonal Surface-Enhanced Raman Scattering Nanoprobes

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Visible-Light-Promoted Oxo-Sulfonylation of Ynamides with Sulfonic Acids

A visible-light-promoted oxo-sulfonylation of ynamides with sulfonic acids is reported, giving rise to a collection of functionalized α-sulfonylated amides in a straightforward manner. The reaction proceeds sequentially through a cascade of electrophilic addition and photoinduced sulfonyl radical-sustained skeleton rearrangement. The high atom economy, mild reaction conditions, and wide substrate scope comprised the merits of this synthetic transformation.