22608-86-2

Basic information

• Product Name: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-ACETAMIDE
• Synonyms: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-ACETAMIDE
• CAS NO: 22608-86-2
• Molecular Formula: C₁₁H₁₃NO₄
• Molecular Weight: 223.23
• Mol File: 22608-86-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-ACETAMIDE(22608-86-2)
• EPA Substance Registry System: N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-ACETAMIDE(22608-86-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 22608-86-2(Hazardous Substances Data)

Usage

Description

N-(2-Formyl-4,5-dimethoxy-phenyl)-acetamide is a chemical compound with the molecular formula C11H13NO4. It is a derivative of acetamide and features a benzene ring with two methoxy groups and a formyl group attached to it. N-(2-FORMYL-4,5-DIMETHOXY-PHENYL)-ACETAMIDE is widely utilized in organic synthesis and serves as a building block for the preparation of various pharmaceuticals. It holds promise in the field of medicinal chemistry, particularly for the development of new drugs with potential analgesic or anti-inflammatory properties. Furthermore, it may also find applications in the development of new materials or in other industrial processes.

Uses

Used in Pharmaceutical Industry:
N-(2-Formyl-4,5-dimethoxy-phenyl)-acetamide is used as a key intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs with analgesic or anti-inflammatory properties. Its unique structure allows for the creation of compounds that can effectively target and alleviate pain or reduce inflammation in the body.
Used in Organic Synthesis:
In the field of organic synthesis, N-(2-Formyl-4,5-dimethoxy-phenyl)-acetamide is used as a building block for the preparation of a variety of complex organic compounds. Its versatility in chemical reactions makes it a valuable component in the synthesis of diverse molecules with potential applications in various industries.
Used in Medicinal Chemistry Research:
N-(2-Formyl-4,5-dimethoxy-phenyl)-acetamide is utilized in medicinal chemistry research as a starting material for the design and development of novel drug candidates. Its structural features enable researchers to explore new avenues in drug discovery, potentially leading to the creation of innovative therapeutic agents.
Used in Material Science:
Although not explicitly mentioned in the provided materials, the potential applications of N-(2-Formyl-4,5-dimethoxy-phenyl)-acetamide in material science could be explored due to its unique chemical structure. It may contribute to the development of new materials with specific properties, such as improved stability, reactivity, or other desirable characteristics for various industrial applications.

Upstream product

• 108-24-7 acetic anhydride 
• 22608-87-3 2-amino-4,5-dimethoxybenzaldehyde 
• 75-36-5 acetyl chloride 
• 63190-11-4 (3,4-dimethoxy-6-nitro-benzyliden)-aniline 
• 5653-40-7 2-Amino-4,5-dimethoxybenzoic acid 
• 1158910-11-2 N-(2-hydroxymethyl-4,5-dimethoxy-phenyl)-acetamide 
• 20357-25-9 6-nitroveratraldehyde 
• 74990-23-1 N-(6,7-dimethoxy-2-methylquinazolin-3-io)-N-amide 

Downstream Products

• 1158909-79-5 N-(2-([2-(2,4-dichloro-phenoxy)-phenylamino]-methyl)-4,5-dimethoxy-phenyl)-acetamide 
• 87880-55-5 4-acetyl-5-(2-amino-4,5-dimethoxyphenyl)-2-(3,4-dimethoxyl)-Δ²-1,3,4-thiadiazoline 
• 87880-53-3 2-(3,4-dimethoxyphenyl)-8,9-dimethoxy-5-methyl-10bH-<1,3,4>thiadiazolo<3,2-c>quinazoline 
• 87880-57-7 2-(3,4-Dimethoxy-phenyl)-7,8-dimethoxy-4-methyl-9bH-1-thia-3,3a,5-triaza-cyclopenta[a]naphthalene; compound with perchloric acid 
• 87880-56-6 4-acetyl-5-(2-acetylamino-4,5-dimethoxyphenyl)-2-(3,4-dimethoxyphenyl)-Δ²-1,3,4-thiadiazoline 
• 5278-38-6 6,7-dimethoxyquinolin-2(1H)-one 
• 92339-95-2 2-acetylamino-4,5-dimethoxybenzaldehyde 4-butylthiosemicarbazone 
• 114284-75-2 (6,7-Dimethoxy-3-phenyl-quinolin-2-yl)-diethyl-amine 

Relevant articles and documents

Cationic Iridium-Catalyzed Asymmetric Decarbonylative Aryl Addition of Aromatic Aldehydes to Bicyclic Alkenes

We report an unprecedented catalytic protocol for the enantioselective decarbonylative transformation of aryl aldehydes. In this process, the decarbonylation of aldehydes catalyzed by chiral iridium complexes enabled the formation of asymmetric C?C bonds

Furan ring opening-indole ring closure: Synthesis of furo[2′, 3′:3,4]-cycloheota[1,2-b]indolium chlorides

A new synthetic approach to furo[2′,3′:3,4]cyclohepta[1,2-b] indolium chlorides is elaborated starting from 2-acetylaminoaryldifurylmethanes or 2-aminoaryldifurylmethanes under treatment with methanolic HCl solution. The reaction proceeds in three steps: recyclization, intramolecular cyclization, and disproportionation. In this case the furan ring takes part in building up both pyrrole and seven-membered rings. The same salts can be obtained directly from 2-acetylaminobenzaldehydes and 2-methylfuran under similar conditions without isolation of corresponding 2-acetylaminoaryldifurylmethanes.

Electron Deficient Heteroaromatic Ammonioamidates. Part 26. N-(Quinazolin-3-io)amidates. Part 13. Phototransformations of an N-(Quinazolin-3-io)thioamidate and of a 10bH-1,3,4-thiadiazoloquinazoline, the Ring Isomer of an N-(Quinazolin-3-io)thioamidate, and the Photochemical Fo

Irradiation of the N-(quinazolin-3-io)thioamidate (10a) in ethanol and butylamine solution furnished, in addition to several other compounds, the 4,4'-biquinazolinyl (12a), the quinazolinyl alcohol (13a) and the quinazolinyl ketone (13b), respectively, the mesoionic triazoloquinazolinylium thiolate (18a) and the corresponding olate (18b) as novel type photolysis products.In contrast, irradiation of the 10bH-1,3,4-thiadiazoloquinazoline (11b), the ring isomer of the N-(quinazolin-3-io)thioamidate (10b) furnishes, with cleavage of either the quinazoline or the thiadiazole ring , a mixture of the thiadiazoles (21a,b), and the quinazoline derivatives (14a), (22a,b) in addition to 3,4-dimethoxybenzonitrile.Irradiation of various sulphur-containing quinazoline derivatives, including the quinazolinethiones (14a,e), the methylthioquinazoline (13f) and the diquinazolinyl disulphide (24a), leads to the formation of 4,4'-biquinazolinyls (12a) and (12b), respectively.Irradiation of the quinazoline (13c), which carries no sulphur-containing substituent, does not lead to the formation of the biquinazolinyl (12a); irradiation of a mixture of quinazoline (13e) and quinazolinethione (14a) gives rise to the formation of a mixture of biquinazolinyls (12a-c) with incorporation of the ring of the sulphur-free starting quinazoline (13e) into the products (12a) and (12b).