227079-00-7

Basic information

• Product Name: (1R,2S)-2-acetoxy-1-indanol
• Synonyms: (1R,2S)-2-acetoxy-1-indanol
• CAS NO: 227079-00-7
• Molecular Weight: 192.214
• Mol File: 227079-00-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S)-2-acetoxy-1-indanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-2-acetoxy-1-indanol(227079-00-7)
• EPA Substance Registry System: (1R,2S)-2-acetoxy-1-indanol(227079-00-7)

Safety Data

• Hazardous Substances Data: 227079-00-7(Hazardous Substances Data)

Upstream product

• 108-05-4 vinyl acetate 
• 4370-02-9 cis-indane-1,2-diol 

Downstream Products

• 136030-00-7 (1R,2S)-1-Amino-2-indanol 

Relevant articles and documents

Lipase-mediated kinetic resolution of cis-1,2-indandiol and the Ritter reaction of its mono-acetate

Lipase-mediated kinetic resolution of cis-1,2-indandiol 5 in the presence of lipase PS was examined. Enantiomerically enriched (1S,2R)-2-acetoxy-1-indanol 6a was obtained when cis-1,2-indandiol 5 was treated with one equivalent of vinyl acetate. Treatment of 5 with two equivalents of vinyl acetate furnished a mixture of (1R,2S)-2-acetoxy-1-indanol 6a and (1R,2S)-1-acetoxy-2-indanol 6b. A route to both enantiomers of 1 was also developed by using the enantiomerically enriched mono-acetate thus obtained.