22713-97-9

Basic information

• Product Name: 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-
• Synonyms: 1,2,4-Thiadiazole,3,5-dianilino- (6CI,7CI,8CI); 1,2,4-Thiadiazole-3,5-diamine, N,N'-diphenyl-(9CI); 3,5-Dianilino-1,2,4-thiadiazole; Dost's base
• CAS NO: 22713-97-9
• Molecular Formula: C14H12 N4 S
• Molecular Weight: 268.342
• Mol File: 22713-97-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-(22713-97-9)
• EPA Substance Registry System: 1,2,4-Thiadiazole-3,5-diamine,N3,N5-diphenyl-(22713-97-9)

Safety Data

• Hazardous Substances Data: 22713-97-9(Hazardous Substances Data)

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 103-85-5 monophenylthiourea 
• 67-66-3 chloroform 
• 22713-99-1 N-phenyl-N'-phenylcarbamimidoyl-thiourea 
• 7726-95-6 bromine 
• 4115-26-8 5-imino-4-phenyl-3-phenylamino-4,5-dihydro-1,2,4-thiadiazoline 
• 7664-41-7 ammonia 
• 35746-67-9 3-(benzylthio)-N-phenyl-1,2,4-thiadiazol-5-amine 
• 62-53-3 aniline 
• 106-49-0 p-toluidine 

Downstream Products

• 14779-22-7 3,5-bis(N-methylphenylamino)-1,2,4-thiadiazole 

Relevant articles and documents

Oxidative azacyclization of 1-monosubstituted thioureas in reaction with [bis(acyloxy)iodo]arenes to form 1,2,4-thiadiazole derivatives

For the first time, derivatives of 1,2,4-thiadiazoles have been obtained by the reaction of [bis(acyloxy)iodo]arenes with 1-monosubstituted thioureas. 1-Acetylthiourea is subject to intermolecular azacyclization to form 3,5-bis-(acetylamino)-1,2,4-thiadia

Synthesis of 5-Amino and 3,5-Diamino Substituted 1,2,4-Thiadiazoles by I2-Mediated Oxidative N-S Bond Formation

An oxidative N-S bond formation reaction has been established for 1,2,4-thiadiazole synthesis employing molecular iodine as the sole oxidant. The features of the present reaction include no use of transition metals, mild reaction conditions, simple operat