227184-11-4 Usage
Description
6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is an organic chemical compound with the chemical formula C6H7FN2O. It is a pyrimidinone derivative with a fluorine-containing ethyl group attached to the sixth carbon in the pyrimidinone ring. 6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is commonly used in pharmaceutical research and drug development as a building block for the synthesis of various bioactive molecules and pharmaceuticals. Its unique structural features and reactivity make it a valuable intermediate in organic synthesis, particularly in the development of potential drug candidates for various therapeutic applications. Furthermore, its fluorine-containing moiety makes it an important functional group for the development of fluorinated pharmaceuticals, which often exhibit improved properties and biological activity compared to non-fluorinated analogs.
Uses
Used in Pharmaceutical Research and Drug Development:
6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is used as a building block for the synthesis of various bioactive molecules and pharmaceuticals. Its unique structural features and reactivity make it a valuable intermediate in organic synthesis, particularly in the development of potential drug candidates for various therapeutic applications.
Used in the Development of Fluorinated Pharmaceuticals:
6-(1-FLUOROETHYL)-4(1H)-PYRIMIDINONE is used as an important functional group for the development of fluorinated pharmaceuticals. The presence of a fluorine-containing moiety often results in improved properties and biological activity compared to non-fluorinated analogs, making it a valuable component in the design and synthesis of novel drug molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 227184-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,7,1,8 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 227184-11:
(8*2)+(7*2)+(6*7)+(5*1)+(4*8)+(3*4)+(2*1)+(1*1)=124
124 % 10 = 4
So 227184-11-4 is a valid CAS Registry Number.
227184-11-4Relevant articles and documents
4-fluoro-3-oxocarboxylic esters and process for producing the same
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, (2008/06/13)
The present invention is to provide 4-fluoro-3-oxocarboxylates represented by the following formula (1): wherein R1represents an alkyl group or an aryl group; R2and R3each represent a hydrogen atom or an alkyl group; and R4represents an alkyl group, and a process for preparing a 4-fluoro-3-oxocarboxylate represented by the above formula (1), which comprises allowing a 2-fluorocarboxylate represented by the following formula (2): wherein R1and R2have the same meanings as defined above; and R5represents an alkyl group, to react with a carboxylate represented by the following formula (3): wherein R3and R4have the same meanings as defined above, in the presence of a base.
6-(1-fluoroalkyl)-4-pyrimidones and processes for producing the same
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Example 1, (2008/06/13)
The present invention is to provide a novel 6-(1-fluoroalkyl)-4-pyrimidone represented by the following formula (1): wherein R1represents an alkyl group; R2represents a hydrogen atom or an alkyl group; and R3represents a hydrogen atom, an alkyl group or a chlorine atom, which is important for a synthetic intermediate for aminopyrimidine derivatives which are useful as acaricides, fungicides or nematocides, and processes for producing the same.