2272-55-1Relevant articles and documents
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Seyden-Penne et al.
, p. 2649,2655 (1970)
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Towards a General Understanding of Carbonyl-Stabilised Ammonium Ylide-Mediated Epoxidation Reactions
Novacek, Johanna,Roiser, Lukas,Zielke, Katharina,Robiette, Rapha?l,Waser, Mario
supporting information, p. 11422 - 11428 (2016/08/03)
The key factors for carbonyl-stabilised ammonium ylide-mediated epoxidation reactions were systematically investigated by experimental and computational means and the hereby obtained energy profiles provide explanations for the observed experimental results. In addition, we were able to identify the first tertiary amine-based chiral auxiliary that allows for high enantioselectivities and high yields for such epoxidation reactions.
Method for Preparing Optically Pure (-)-Clausenamide Compound
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Paragraph 0042; 0043; 0044; 0045, (2014/07/23)
Disclosed in the present invention is a method for preparing a (?)-clausenamide compound of formula (I), comprising: firstly, catalyzing the asymmetrical epoxidation of trans-cinnamate using a chiral ketone derived from fructose or a hydrate thereof as a catalyst, and then subjecting the product to transesterification, oxidation, cyclization and reduction successively to finally obtain the optically pure (?)-clausenamide compound of formula (I).