22748-59-0

Basic information

• Product Name: 1-Butanone,3-methyl-1-[2,4,6-trihydroxy-3,5-bis(3-methylbutyl)phenyl]-
• Synonyms: Butyrophenone,2',4',6'-trihydroxy-3',5'-diisopentyl-3-methyl- (8CI); Phlorobutyrophenone,3',5'-diisopentyl-3-methyl- (6CI); 4-Deoxytetrahydrohumulone;Ethoxytetrahydrohumulone; Humulone, 4-deoxytetrahydro-
• CAS NO: 22748-59-0
• Molecular Formula: C21H34 O4
• Molecular Weight: 350.499
• Mol File: 22748-59-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Butanone,3-methyl-1-[2,4,6-trihydroxy-3,5-bis(3-methylbutyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone,3-methyl-1-[2,4,6-trihydroxy-3,5-bis(3-methylbutyl)phenyl]-(22748-59-0)
• EPA Substance Registry System: 1-Butanone,3-methyl-1-[2,4,6-trihydroxy-3,5-bis(3-methylbutyl)phenyl]-(22748-59-0)

Safety Data

• Hazardous Substances Data: 22748-59-0(Hazardous Substances Data)

Upstream product

• 4374-93-0 deoxyhumulone 
• 26104-03-0 2,4-Diisopentyl-phloroglucin 
• 108-12-3 isopentanoyl chloride 
• 26103-97-9 phloroisovalerophenone 
• 870-63-3 prenyl bromide 
• 108-73-6 3,5-dihydroxyphenol 
• 26104-00-7 1-isopentyl-2,4,6-trihydroxybenzene 
• 26104-01-8 3-methyl-1-(2,4,6-trihydroxy-3-isopentylphenyl)butan-1-one 

Downstream Products

• 1374228-87-1 (-)-tetrahydrohumulone 
• 26472-42-4 (+)-tetrahydrohumulone 
• 1374228-90-6 tetrahydrohumulone 
• 26272-23-1 (+/-)-Tetrahydrohumulon 

Relevant articles and documents

Methods of synthesizing alpha acids and substantially enantiomerically pure compositions thereof

Methods of synthesizing a cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one (“KDT500”) derivative are provided. Such methods may be used to synthesize any desired KDT derivative. In one embodiment, the KDT500 derivative is KDT501.

CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS

The present application provides cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one derivatives and substantially enantiomerically pure compositions thereof. These derivatives include (+)-(4S,5R)-3,4-dihydro